Literature summary for 2.4.1.68 extracted from

Manabe, Y.; Kasahara, S.; Takakura, Y.; Yang, X.; Takamatsu, S.; Kamada, Y.; Miyoshi, E.; Yoshidome, D.; Fukase, K.
Development of alpha1,6-fucosyltransferase inhibitors through the diversity-oriented syntheses of GDP-fucose mimics using the coupling between alkyne and sulfonyl azide (2017), Bioorg. Med. Chem., 25, 2844-2850 .

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Inhibitors

Inhibitors	Comment	Organism	Structure
methyl (1Z)-N-[[5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)pentyl]sulfanyl]-3-[(beta-L-fucopyranosyl)oxy]propanimidate	analogue of guanosine 5'-diphospho-beta-L-fucose. 57% inhibition at 0.1 microM	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q9BYC5	isoform FUT8	-

Synonyms

Synonyms	Comment	Organism
FUT8	-	Homo sapiens

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Release 2023.1 (January 2023)