Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.4.1.65 extracted from

  • Legault, D.J.; Kelly, R.J.; Natsuka, Y.; Lowe, J.B.
    Human alpha(1,3/1,4)-fucosyltransferases discriminate between different oligosaccharide acceptor substrates through a discrete peptide fragment (1995), J. Biol. Chem., 270, 20987-20996.
    View publication on PubMed

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
8.1
-
Galbeta(1,4)GlcNAc
-
Homo sapiens
12.7
-
Galbeta(1,3)GlcNAc
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GDP-L-fucose + Galbeta(1,3)GlcNAc
-
Homo sapiens GDP + Galbeta(1,3)(Fucalpha(1,4))GlcNAc
-
?
GDP-L-fucose + Galbeta(1,4)GlcNAc i.e. N-acetyllactosamine Homo sapiens GDP + Galbeta(1,4)(Fucalpha(1,3))GlcNAc
-
?
additional information 11 nonidentical amino acids, found within a hypervariable peptide segment positioned at the NH2 terminus determins whether or not a alpha(1,3)-fucosyltransferase can utilize type I acceptor substrates to form Lewis a and sialyl Lewis a moieties Homo sapiens ?
-
?