Literature summary for 2.4.1.46 extracted from

Botte, C.Y.; Deligny, M.; Roccia, A.; Bonneau, A.L.; Saidani, N.; Hardre, H.; Aci, S.; Yamaryo-Botte, Y.; Jouhet, J.; Dubots, E.; Loizeau, K.; Bastien, O.; Brehelin, L.; Joyard, J.; Cintrat, J.C.; Falconet, D.; Block, M.A.; Rousseau, B.; Lopez, R.; Marechal, E.
Chemical inhibitors of monogalactosyldiacylglycerol synthases in Arabidopsis thaliana (2011), Nat. Chem. Biol., 7, 834-842.

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Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli BL21	Arabidopsis thaliana

Inhibitors

Inhibitors	Comment	Organism	Structure
galvestine-1	competitive to diacylglycerol	Arabidopsis thaliana
galvestine-2	-	Arabidopsis thaliana

Organism

Organism	UniProt	Comment	Textmining
Arabidopsis thaliana	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
UDP-galactose + 1,2-diacylglycerol	-	Arabidopsis thaliana	UDP + 3-beta-D-galactosyl-1,2-diacyl-sn-glycerol	-	?

Synonyms

Synonyms	Comment	Organism
monogalactosyldiacylglycerol synthase 1	-	Arabidopsis thaliana

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.01	-	pH 7.8, temperature not specified in the publication	Arabidopsis thaliana	galvestine-1
0.012	-	pH 7.8, temperature not specified in the publication	Arabidopsis thaliana	galvestine-2

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Release 2023.1 (January 2023)