Cloned (Comment) | Organism |
---|---|
expressed in COS-7 cells | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
E334Q | the mutant shows strongly reduced activity compared to the wild type enzyme | Homo sapiens |
N335A | the mutant shows strongly reduced activity compared to the wild type enzyme | Homo sapiens |
N335D | the mutant shows strongly reduced activity compared to the wild type enzyme | Homo sapiens |
N335H | the mutant shows strongly reduced activity compared to the wild type enzyme | Homo sapiens |
N335S | the mutant shows strongly reduced activity compared to the wild type enzyme | Homo sapiens |
R362K | the mutant shows strongly reduced activity compared to the wild type enzyme | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | no activity with 2'-deoxy-alpha-D-galactosamine or 2'-oxymethyl-alpha-D-galactosamine | ? | - |
? | |
UDP-N-acetyl-alpha-D-galactosamine + polypeptide EA2 | Homo sapiens | sequence PTTDSTTPAPTTK | UDP + N-acetyl-alpha-D-galactosaminyl-polypeptide EA2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q10471 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | no activity with 2'-deoxy-alpha-D-galactosamine or 2'-oxymethyl-alpha-D-galactosamine | Homo sapiens | ? | - |
? | |
UDP-N-acetyl-alpha-D-galactosamine + polypeptide EA2 | sequence PTTDSTTPAPTTK | Homo sapiens | UDP + N-acetyl-alpha-D-galactosaminyl-polypeptide EA2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
GalNAc-T2 | - |
Homo sapiens |
UDP-GalNAc polypeptide:GalNAc transferase-T2 | - |
Homo sapiens |
UDP-N-acetylgalactosamine polypeptide: N-acetylgalactosaminyl-transferase | - |
Homo sapiens |