Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-N-acetyl-alpha-D-galactosamine + polypeptide MUC13 | Homo sapiens | isoform GALNT14 contributes to the glycosylation of peptide MUC13, which is significantly higher in ovarian cancer cells compared with the normal/benign ovary tissues | UDP + N-acetyl-alpha-D-galactosaminyl-polypeptide MUC13 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HO-8910 cell | - |
Homo sapiens | - |
HO-8910PM | - |
Homo sapiens | - |
OVCAR-3 cell | - |
Homo sapiens | - |
SKOV-3 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-N-acetyl-alpha-D-galactosamine + polypeptide MUC13 | isoform GALNT14 contributes to the glycosylation of peptide MUC13, which is significantly higher in ovarian cancer cells compared with the normal/benign ovary tissues | Homo sapiens | UDP + N-acetyl-alpha-D-galactosaminyl-polypeptide MUC13 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
GALNT14 | - |
Homo sapiens |
polypeptide N-acetylgalactosaminyltransferase 14 | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | interleukin-8 has no remarkable effect on the expression of isoform GALNT14 | additional information |
Homo sapiens | extracellular signal-regulated kinase 1/2 inhibitor modulates the expression levels of isoform GALNT14 | up |
General Information | Comment | Organism |
---|---|---|
physiological function | isoform GALNT14 contributes to ovarian carcinogenesis through aberrant glycosylation of MUC13, but not through the interleukin-8 pathway | Homo sapiens |