Application | Comment | Organism |
---|---|---|
molecular biology | enzyme-linked lectin assay (ELLA) as carbohydrate-binding assay | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
in pAcGP67-His vector for amplification as bacculovirus in Sf9 cells and subsequent infection of High Five cells | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
GalNAc-T2 lectin domain | amino acids 405 to 578 of GalNAc-T2, lower expression level than full-length enzyme | Homo sapiens |
GalNAc-T2-D224H | mutation in DXH nucleotide-binding motif, inactive mutant | Homo sapiens |
GalNAc-T2-D458H | mutation in CLD motif of alpha repeat, impaired lectin-mediated MUC1 and GalNAc-MUC1 binding, no impaired specific activity, incorporates 1-2 fewer GalNAc residues per substrate molecule in endpoint reactions, no utilization of partially GalNAc-glycosylated peptides, higher KM for IgA hinge-4GalNAc | Homo sapiens |
GalNAc-T2-D541A | mutation in CLD motif of gamma repeat | Homo sapiens |
GalNAc-T4 lectin domain | amino acids 432 to 571 of GalNAc-T4, lower expression level than full-length enzyme | Homo sapiens |
GalNAc-T4 lectin domain-D459H | mutation in CLD motif of alpha repeat | Homo sapiens |
GalNAc-T4-D459H | mutation in CLD motif of alpha repeat, impaired lectin-mediated MUC1 and GalNAc-MUC1 binding | Homo sapiens |
General Stability | Organism |
---|---|
23% loss of specific activity after 12h shaking at 37°C | Homo sapiens |
25% loss of specific activity after 12 h shaking at 37°C | Homo sapiens |
31% loss of specific activity after 12h shaking at 37°C | Homo sapiens |
mutant GalNAc-T2-D458H: 15% loss of specific activity after 12h shaking at 37°C | Homo sapiens |
mutant GalNAc-T2-D541A: 19% loss of specific activity after 12h shaking at 37°C | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
benzyl-alpha-GalNAc | - |
Homo sapiens | |
D-galactose | - |
Homo sapiens | |
EDTA | GalNAc-T4 enzyme and lectin domain; inhibition of GalNAc-T2 enzyme and lectin domain | Homo sapiens | |
GalNAc | inhibition for GalNAc-T2 lectin domain to bind GalNAc-MUC1; inhibition for GalNAc-T4 lectin domain to bind GalNAc-MUC1 | Homo sapiens | |
methyl-alpha-Gal | - |
Homo sapiens | |
methyl-beta-Gal | - |
Homo sapiens | |
additional information | benzyl or phenyl alpha and beta-GalNAc compounds show higher inhibition for GalNAc-T2 to bind GalNAc-MUC1 than for isoform GalNAc-T4. No inhibition of GalNAc-T2 enzyme and lectin domain by glucose, GlcNAc or mannose; benzyl or phenyl alpha and beta-GalNAc compounds show weaker inhibition for GalNAc-T4 to bind GalNAc-MUC1 than for isoform GalNAc-T2. No inhibition of GalNAc-T4 enzyme and lectin domain by glucose, GlcNAc or mannose | Homo sapiens | |
o-nitrophenyl-alpha-GalNAc | - |
Homo sapiens | |
o-nitrophenyl-beta-GalNAc | - |
Homo sapiens | |
p-nitrophenyl-alpha-GalNAc | - |
Homo sapiens | |
p-nitrophenyl-beta-GalNAc | - |
Homo sapiens | |
phenyl-alpha-GalNAc | - |
Homo sapiens | |
UDP-alpha-GalNAc | - |
Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.01 | - |
Muc2 | +/-0.001 mM, pH7.4 | Homo sapiens | |
0.01 | - |
IgA hinge | +/-0.01 mM, mutant GalNAc-T2-D541A, pH7.4 | Homo sapiens | |
0.011 | - |
UDP-GalNAc | +/-0.002 mM, pH7.4 | Homo sapiens | |
0.013 | - |
UDP-GalNAc | +/-0.001 mM, mutant GalNAc-T2-D541A, pH7.4 | Homo sapiens | |
0.015 | - |
IgA hinge | +/-0.002 mM, pH7.4 | Homo sapiens | |
0.018 | - |
Muc2 | +/-0.003 mM, mutant GalNAc-T2-D541A, pH7.4 | Homo sapiens | |
0.02 | - |
IgA hinge | +/-0.005 mM, mutant GalNAc-T2-D458H, pH7.4 | Homo sapiens | |
0.03 | - |
UDP-GalNAc | +/-0.001 mM, mutant GalNAc-T2-D458H, pH7.4 | Homo sapiens | |
0.03 | - |
UDP-Gal | +/-0.002 mM, pH7.4 | Homo sapiens | |
0.036 | - |
UDP-Gal | +/-0.001 mM, mutant GalNAc-T2-D458H, pH7.4 | Homo sapiens | |
0.041 | - |
UDP-Gal | +/-0.005 mM, mutant GalNAc-T2-D541A, pH7.4 | Homo sapiens | |
0.062 | - |
MUC2-6GalNAc | +/-0.007 mM, pH7.4 | Homo sapiens | |
0.066 | - |
MUC2-6GalNAc | +/-0.010 mM, mutant GalNAc-T2-D541A, pH7.4 | Homo sapiens | |
0.12 | - |
IgA hinge-4GalNAc | +/-0.01 mM, pH7.4 | Homo sapiens | |
0.15 | - |
MUC1 | +/-0.03 mM, mutant GalNAc-T2-D541A, pH7.4 | Homo sapiens | |
0.25 | - |
Muc2 | +/-0.006 mM, mutant GalNAc-T2-D458H, pH7.4 | Homo sapiens | |
0.26 | - |
MUC1 | +/-0.16 mM, pH7.4 | Homo sapiens | |
0.32 | - |
IgA hinge-4GalNAc | +/-0.09 mM, mutant GalNAc-T2-D541A, pH7.4 | Homo sapiens | |
0.36 | - |
MUC1 | +/-0.19mM, mutant GalNAc-T2-D458H, pH7.4 | Homo sapiens | |
0.81 | - |
IgA hinge-4GalNAc | +/-0.2 mM, mutant GalNAc-T2-D458H, pH7.4 | Homo sapiens | |
0.86 | - |
MUC1-2GalNAc | +/-0.21 mM, mutant GalNAc-T2-D541A, pH7.4 | Homo sapiens | |
0.87 | - |
MUC1-2GalNAc | +/-0.23 mM, pH7.4 | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
intracellular | CHO ldlD-MUC1 cells in presence of GalNAc | Homo sapiens | 5622 | - |
intracellular | CHO ldlD-MUC1 cells in presence of GalNAc: same pattern of biotinylated GalNAc-T2 like Tn (GalNAc-alpha-Ser/Thr) | Homo sapiens | 5622 | - |
intracellular | CHO ldlD-MUC1 cells in presence of GalNAc: same pattern of biotinylated GalNAc-T4 and -T4 lectin like Tn (GalNAc-alpha-Ser/Thr) | Homo sapiens | 5622 | - |
intracellular | human salivary glands | Homo sapiens | 5622 | - |
intracellular | human salivary glands: same pattern of biotinylated GalNAc-T2 at Golgi-like supranuclear locations like Tn (GalNAc-alpha-Ser/Thr) | Homo sapiens | 5622 | - |
intracellular | human salivary glands: same pattern of biotinylated GalNAc-T4 lectin at Golgi-like supranuclear locations like Tn (GalNAc-alpha-Ser/Thr) | Homo sapiens | 5622 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-N-acetyl-D-galactosamine + polypeptide | Homo sapiens | mucin-type O-linked glycosylation of serine or threonine residues | UDP + N-acetyl-D-galactosaminyl-polypeptide | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q10471 | GalNAc-T2 | - |
Homo sapiens | Q10472 | GalNAc-T1 | - |
Homo sapiens | Q8N4A0 | GalNAc-T4 | - |
Homo sapiens | Q8NCW6 | GalNAc-T11 | - |
Purification (Comment) | Organism |
---|---|
purification of His-tagged truncated lectin domain by IMAC, 250 mM imidazole | Homo sapiens |
purification of secreted recombinant proteins from cell culture supernatant by Amberlite IRA-95 chromatography followed by SP Sepharose Fast Flow ion-exchange chromatography and concentrated by centrifugation through 10000 Da cut-off filter followed by elution from a PC3.2/3 column | Homo sapiens |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
0.005 +/-0.007 micromol/min/ml, MUC1-2GalNaC by mutant GalNAc-T2-D458H, pH7.4 | Homo sapiens |
additional information | - |
0.018 +/-0.003 micromol/min/ml, MUC7, pH7.4 | Homo sapiens |
additional information | - |
0.018 +/-0.004 micromol/min/ml, MUC1-b, pH7.4 | Homo sapiens |
additional information | - |
0.025 +/-0.008 micromol/min/ml, MUC1-2GalNAC, pH7.4 | Homo sapiens |
additional information | - |
0.028 +/-0.011 micromol/min/ml, MUC1-a' by mutant GalNAc-T2-D541A, pH7.4 | Homo sapiens |
additional information | - |
0.029 +/-0.007 micromol/min/ml, MUC1-a' by mutant GalNAc-T2-D458H, pH7.4 | Homo sapiens |
additional information | - |
0.029 +/-0.008 micromol/min/ml, MUC7, pH7.4 | Homo sapiens |
additional information | - |
0.031 +/-0.003 micromol/min/ml, MUC1-a', pH7.4 | Homo sapiens |
additional information | - |
0.036 +/-0.003 micromol/min/ml, MUC7, pH7.4 | Homo sapiens |
additional information | - |
0.039 +/-0.010 micromol/min/ml, erythropoitin T, pH7.4 | Homo sapiens |
additional information | - |
0.046 +/-0.005 micromol/min/ml, MUC7 by mutant GalNAc-T2-D541A, pH7.4 | Homo sapiens |
additional information | - |
0.046 +/-0.006 micromol/min/ml, MUC1-2GalNAC, pH7.4 | Homo sapiens |
additional information | - |
0.046 +/-0.009 micromol/min/ml, MUC2-6GalNAc by mutant GalNAc-T2-D541A, pH7.4 | Homo sapiens |
additional information | - |
0.047 +/-0.011 micromol/min/ml, erythropoitin T by mutant GalNAc-T2-D458H, pH7.4 | Homo sapiens |
additional information | - |
0.051 +/-0.006 micromol/min/ml, hCG-beta, pH7.4 | Homo sapiens |
additional information | - |
0.053 +/-0.010 micromol/min/ml, MUC7 by mutant GalNAc-T2-D458H, pH7.4 | Homo sapiens |
additional information | - |
0.054 +/-0.001 micromol/min/ml, hCG-beta by mutant GalNAc-T2-D458H, pH7.4 | Homo sapiens |
additional information | - |
0.055 +/-0.008 micromol/min/ml, MUC1-2GalNaC by mutant GalNAc-T2-D541A, pH7.4 | Homo sapiens |
additional information | - |
0.062 +/-0.010 micromol/min/ml, MUC2-6GalNAc, pH7.4 | Homo sapiens |
additional information | - |
0.065 +/-0.007 micromol/min/ml, hCG-beta by mutant GalNAc-T2-D541A, pH7.4 | Homo sapiens |
additional information | - |
0.066 +/-0.008 micromol/min/ml, erythropoitin T by mutant GalNAc-T2-D541A, pH7.4 | Homo sapiens |
additional information | - |
0.074 +/-0.005 micromol/min/ml, erythropoitin T, pH7.4 | Homo sapiens |
additional information | - |
0.076 +/-0.003 micromol/min/ml, erythropoitin T, pH7.4 | Homo sapiens |
additional information | - |
0.085 +/-0.003 micromol/min/ml, MUC1-a, pH7.4 | Homo sapiens |
additional information | - |
0.086 +/-0.007 micromol/min/ml, MUC1-a, pH7.4 | Homo sapiens |
additional information | - |
0.087 +/-0.006 micromol/min/ml, MUC1-b', pH7.4 | Homo sapiens |
additional information | - |
0.094 +/-0.008 micromol/min/ml, MUC1-b' by mutant GalNAc-T2-D458H, pH7.4 | Homo sapiens |
additional information | - |
0.097 +/-0.002 micromol/min/ml, MUC1, pH7.4 | Homo sapiens |
additional information | - |
0.108 +/-0.002 micromol/min/ml, OSM fragment, pH7.4 | Homo sapiens |
additional information | - |
0.121 +/-0.013 micromol/min/ml, MUC1 by mutant GalNAc-T2-D458H, pH7.4 | Homo sapiens |
additional information | - |
0.122 +/-0.007 micromol/min/ml, MUC1, pH7.4 | Homo sapiens |
additional information | - |
0.125 +/-0.003 micromol/min/ml, MUC2, pH7.4 | Homo sapiens |
additional information | - |
0.142 +/-0.005 micromol/min/ml, IgA hinge by mutant GalNAc-T2-D541A, pH7.4 | Homo sapiens |
additional information | - |
0.151 +/-0.012 micromol/min/ml, MUC1 by mutant GalNAc-T2-D541A, pH7.4 | Homo sapiens |
additional information | - |
0.158 +/-0.010 micromol/min/ml, MUC1, pH7.4 | Homo sapiens |
additional information | - |
0.161 +/-0.005 micromol/min/ml, IgA hinge, pH7.4 | Homo sapiens |
additional information | - |
0.164 +/-0.007 micromol/min/ml, MUC2 by mutant GalNAc-T2-D458H, pH7.4 | Homo sapiens |
additional information | - |
0.165 +/-0.013 micromol/min/ml, MUC2 by mutant GalNAc-T2-D541A, pH7.4 | Homo sapiens |
additional information | - |
0.185 +/-0.006 micromol/min/ml, IgA hinge by mutant GalNAc-T2-D458H, pH7.4 | Homo sapiens |
additional information | - |
0.224 +/-0.002 micromol/min/ml, IgA hinge, pH7.4 | Homo sapiens |
additional information | - |
0.281 +/-0.013 micromol/min/ml, IgA hinge, pH7.4 | Homo sapiens |
additional information | - |
0.283 +/-0.010 micromol/min/ml, MUC2, pH7.4 | Homo sapiens |
additional information | - |
128 +/-0.007 micromol/min/ml, MUC1-b' by mutant GalNAc-T2-D541A, pH7.4 | Homo sapiens |
additional information | - |
152 +/-0.018 micromol/min/ml, MUC2, pH7.4 | Homo sapiens |
45 | - |
+/-13, UDP-GalNAc by mutant GalNAc-T2-D458H, pH7.4 | Homo sapiens |
46 | - |
+/-12, UDP-GalNAc by mutant GalNAc-T2-D541A, pH7.4 | Homo sapiens |
49 | - |
+/-5, IgA hinge-4GalNAc by mutant GalNAc-T2-D541A, pH7.4 | Homo sapiens |
56 | - |
+/-6, UDP-Gal, pH7.4 | Homo sapiens |
65 | - |
+/-5, UDP-Gal by mutant GalNAc-T2-D458H, pH7.4 | Homo sapiens |
69 | - |
+/-12, UDP-GalNAc, pH7.4 | Homo sapiens |
72 | - |
+/-21, MUC1-2GalNAc, pH7.4 | Homo sapiens |
81 | - |
+/-1, MUC2, pH7.4 | Homo sapiens |
83 | - |
+/-13, IgA hinge-4GalNAc, pH7.4 | Homo sapiens |
85 | - |
+/-5, UDP-Gal by mutant GalNAc-T2-D541A, pH7.4 | Homo sapiens |
94 | - |
+/-5, MUC1 by mutant GalNAc-T2-D458H, pH7.4 | Homo sapiens |
97 | - |
+/-14, MUC1, pH7.4 | Homo sapiens |
118 | - |
+/-39, MUC1-2GalNAc by mutant GalNAc-T2-D541A, pH7.4 | Homo sapiens |
119 | - |
+/-24, IgA hinge-4GalNAc by mutant GalNAc-T2-D458H, pH7.4 | Homo sapiens |
143 | - |
+/-15, MUC1 by mutant GalNAc-T2-D541A, pH7.4 | Homo sapiens |
145 | - |
+/-21, IgA hinge by mutant GalNAc-T2-D541A, pH7.4 | Homo sapiens |
150 | - |
+/-6, MUC2 by mutant GalNAc-T2-D458H, pH7.4 | Homo sapiens |
236 | - |
+/-1, IgA hinge by mutant GalNAc-T2-D458H, pH7.4 | Homo sapiens |
273 | - |
+/-12, MUC2 by mutant GalNAc-T2-D541A, pH7.4 | Homo sapiens |
292 | - |
+/-18, MUC2-6GalNAc by mutant GalNAc-T2-D541A, pH7.4 | Homo sapiens |
302 | - |
+/-17, MUC2-6GalNAc, pH7.4 | Homo sapiens |
321 | - |
+/-18, IgA hinge, pH7.4 | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
erythropoietin T + UDP-Gal | - |
Homo sapiens | erythropoietin T-nGalNAc + UDP | - |
? | |
erythropoietin T + UDP-Gal | also catalysed by mutants GalTNAc-T2-D458H and GalTNAc-T2-D541A | Homo sapiens | erythropoietin T-nGalNAc + UDP | - |
? | |
hCG-beta + UDP-Gal | - |
Homo sapiens | hCG-beta-nGalNAc + UDP | - |
? | |
IgA hinge + UDP-Gal | - |
Homo sapiens | IgA hinge-nGal + UDP | - |
? | |
IgA hinge + UDP-GalNAc | - |
Homo sapiens | IgA hinge-nGalNAc + UDP | - |
? | |
IgA hinge + UDP-GalNAc | GalTNAc-T11 incorporates only two GalNAc residues into IgA hinge peptide | Homo sapiens | IgA hinge-nGalNAc + UDP | - |
? | |
IgA hinge + UDP-GalNAc | mutant GalNAc-T2-D458H incorporates 1-2 fewer GalNAc residues than wild-type | Homo sapiens | IgA hinge-nGalNAc + UDP | - |
? | |
IgA hinge-4GalNAc + UDP-GalNAc | - |
Homo sapiens | IgA hinge-nGalNAc + UDP | - |
? | |
additional information | MUC1-2GalNAc, MUC2-6GalNAc, OSM fragments, hCG-beta are not substrates for GalNAc-T11 | Homo sapiens | ? | - |
? | |
additional information | MUC1b' and hCG-beta are no substrates for GalNAc-T1 | Homo sapiens | ? | - |
? | |
MUC1 + UDP-GalNAc | - |
Homo sapiens | MUC1-nGalNAc + UDP | - |
? | |
MUC1 + UDP-GalNAc | GalNAc-T4 lectin domain does not exhibit selective specificities for peptide sequences, or the density or pattern of GalNAc glycosylation, GalNAc-T4 lectin domain mediates GalNAc-glycopeptide substrate specificity | Homo sapiens | MUC1-nGalNAc + UDP | - |
? | |
MUC1 + UDP-GalNAc | mutant GalNAc-T2-D458H incorporates 1-2 fewer GalNAc residues than wild-type, GalNAc-T2 lectin domain does not exhibit selective specificities for peptide sequences, or the density or pattern of GalNAc glycosylation | Homo sapiens | MUC1-nGalNAc + UDP | - |
? | |
MUC1-2GalNAc + UDP-GalNAc | - |
Homo sapiens | MUC1-nGalNAc + UDP | - |
? | |
MUC1a' + UDP-GalNAc | - |
Homo sapiens | MUC1a'-nGalNAc + UDP | - |
? | |
MUC1b' + UDP-GalNAc | - |
Homo sapiens | MUC1b'-nGalNAc + UDP | - |
? | |
MUC2 + UDP-GalNAc | - |
Homo sapiens | MUC2-nGalNAc + UDP | - |
? | |
MUC2-6GalNAc + UDP-GalNAc | - |
Homo sapiens | MUC2-nGalNAc + UDP | - |
? | |
MUC7 + UDP-GalNAc | - |
Homo sapiens | MUC7-nGalNAc + UDP | - |
? | |
OSM fragment + UDP-Gal | - |
Homo sapiens | OSM fragment-nGalNAc + UDP | - |
? | |
UDP-N-acetyl-D-galactosamine + polypeptide | mucin-type O-linked glycosylation of serine or threonine residues | Homo sapiens | UDP + N-acetyl-D-galactosaminyl-polypeptide | - |
? |
Synonyms | Comment | Organism |
---|---|---|
(UDP)-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase | - |
Homo sapiens |
GalNAc transferase | - |
Homo sapiens |
GalNAc-T | - |
Homo sapiens |
UDP GalNAc:polypeptide N-acetylgalactosaminyltransferase | - |
Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
additional information | - |
EDTA exhibits IC50 higher than 10 in all cases | Homo sapiens | additional information | |
additional information | - |
EDTA exhibits IC50s higher than 10 in all cases | Homo sapiens | additional information | |
additional information | - |
galactose and methyl-alpha/beta-Gal exhibit IC50 higher than 100 mM for GalNAc-T2 enzyme and lectin domain | Homo sapiens | additional information | |
additional information | - |
galactose and methyl-alpha/beta-Gal exhibit IC50s higher than 100 mM for GalNAc-T4 lectin domain | Homo sapiens | additional information | |
additional information | - |
GalNAc-T2 lectin domain exhibits no specificity for anomeric configuration of GalNAc according to simlar IC50s | Homo sapiens | additional information | |
additional information | - |
GalNAc-T4 lectin domain exhibits no specificity for anomeric configuration of GalNAc according to simlar IC50s | Homo sapiens | additional information | |
additional information | - |
glucose derivatives, lactose and UDP exhibit IC50 higher than 100 mM in all cases | Homo sapiens | additional information | |
additional information | - |
glucose derivatives, lactose and UDP exhibit IC50s higher than 100 mM in all cases | Homo sapiens | additional information | |
additional information | - |
UDP exhibits similar inhibitory effects on GalNAc-T2 and mutant GalNAc-T2-D458H | Homo sapiens | additional information | |
additional information | - |
UDP-alpha-GalNAc exhibits IC50 higher than 100 mM for GalNAc-T2 lectin domain | Homo sapiens | additional information | |
0.5 | - |
GalNAc-MUC1 binding to biotinylated GalNAc-T4 | Homo sapiens | o-nitrophenyl-alpha-GalNAc | |
0.8 | - |
GalNAc-MUC1 binding to biotinylated GalNAc-T4 | Homo sapiens | p-nitrophenyl-beta-GalNAc | |
1 | - |
GalNAc-MUC1 binding to biotinylated GalNAc-T4 | Homo sapiens | GalNAc | |
1 | - |
GalNAc-MUC1 binding to biotinylated GalNAc-T4 | Homo sapiens | benzyl-alpha-GalNAc | |
1 | - |
GalNAc-MUC1 binding to biotinylated GalNAc-T4 | Homo sapiens | phenyl-alpha-GalNAc | |
1 | - |
GalNAc-MUC1 binding to biotinylated GalNAc-T4 | Homo sapiens | o-nitrophenyl-beta-GalNAc | |
1 | - |
GalNAc-MUC1 binding to biotinylated GalNAc-T4 | Homo sapiens | p-nitrophenyl-alpha-GalNAc | |
5 | - |
GalNAc-MUC1 binding to biotinylated GalNAc-T2 | Homo sapiens | phenyl-alpha-GalNAc | |
5 | - |
GalNAc-MUC1 binding to biotinylated GalNAc-T4 lectin domain | Homo sapiens | GalNAc | |
5 | - |
GalNAc-MUC1 binding to biotinylated GalNAc-T4 lectin domain | Homo sapiens | benzyl-alpha-GalNAc | |
5 | - |
GalNAc-MUC1 binding to biotinylated GalNAc-T4 lectin domain | Homo sapiens | phenyl-alpha-GalNAc | |
5 | - |
GalNAc-MUC1 binding to biotinylated GalNAc-T4 lectin domain | Homo sapiens | o-nitrophenyl-alpha-GalNAc | |
7 | - |
GalNAc-MUC1 binding to biotinylated GalNAc-T2 | Homo sapiens | o-nitrophenyl-alpha-GalNAc | |
8 | - |
GalNAc-MUC1 binding to biotinylated GalNAc-T4 lectin domain | Homo sapiens | p-nitrophenyl-beta-GalNAc | |
8 | - |
GalNAc-MUC1 binding to biotinylated GalNAc-T4 lectin domain | Homo sapiens | ortho-nitrophenyl-beta-GalNAc | |
10 | - |
GalNAc-MUC1 binding to biotinylated GalNAc-T2 | Homo sapiens | p-nitrophenyl-beta-GalNAc | |
10 | - |
GalNAc-MUC1 binding to biotinylated GalNAc-T2 | Homo sapiens | o-nitrophenyl-beta-GalNAc | |
10 | - |
GalNAc-MUC1 binding to biotinylated GalNAc-T2 | Homo sapiens | p-nitrophenyl-alpha-GalNAc | |
10 | - |
GalNAc-MUC1 binding to biotinylated GalNAc-T2 lectin domain | Homo sapiens | p-nitrophenyl-beta-GalNAc | |
10 | - |
GalNAc-MUC1 binding to biotinylated GalNAc-T2 lectin domain | Homo sapiens | p-nitrophenyl-alpha-GalNAc | |
10 | - |
GalNAc-MUC1 binding to biotinylated GalNAc-T4 lectin domain | Homo sapiens | para-nitrophenyl-alpha-GalNAc | |
12 | - |
GalNAc-MUC1 binding to biotinylated GalNAc-T2 lectin domain | Homo sapiens | o-nitrophenyl-alpha-GalNAc | |
12 | - |
GalNAc-MUC1 binding to biotinylated GalNAc-T2 lectin domain | Homo sapiens | o-nitrophenyl-beta-GalNAc | |
15 | - |
GalNAc-MUC1 binding to biotinylated GalNAc-T2 | Homo sapiens | GalNAc | |
15 | - |
GalNAc-MUC1 binding to biotinylated GalNAc-T2 | Homo sapiens | benzyl-alpha-GalNAc | |
15 | - |
GalNAc-MUC1 binding to biotinylated GalNAc-T2 lectin domain | Homo sapiens | phenyl-alpha-GalNAc | |
20 | - |
GalNAc-MUC1 binding to biotinylated GalNAc-T2 lectin domain | Homo sapiens | benzyl-alpha-GalNAc | |
30 | - |
GalNAc-MUC1 binding to biotinylated GalNAc-T4 | Homo sapiens | UDP-alpha-GalNAc | |
37 | - |
GalNAc-MUC1 binding to biotinylated GalNAc-T2 lectin domain | Homo sapiens | GalNAc | |
40 | - |
GalNAc-MUC1 binding to biotinylated GalNAc-T4 | Homo sapiens | methyl-beta-Gal | |
50 | - |
GalNAc-MUC1 binding to biotinylated GalNAc-T4 | Homo sapiens | D-galactose | |
50 | - |
GalNAc-MUC1 binding to biotinylated GalNAc-T4 | Homo sapiens | methyl-alpha-Gal | |
50 | - |
GalNAc-MUC1 binding to biotinylated GalNAc-T4 lectin domain | Homo sapiens | UDP-alpha-GalNAc | |
65 | - |
GalNAc-MUC1 binding to biotinylated GalNAc-T2 | Homo sapiens | UDP-alpha-GalNAc |