Cloned (Comment) | Organism |
---|---|
GalNAc-T9 is cloned and characterized encoding a 603 amino acid protein, nucleotide and amino acid sequence | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | GalNAc-T9: type II membrane protein with a 20-amino acid transmembrane domain, a 7-amino acid cytoplasmic domain and a 91-amino acid stem region | Homo sapiens | 16020 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-N-acetyl-D-galactosamine + polypeptide | Homo sapiens | GalNAc-T9 catalyzes O-glycosylation in brain | UDP + N-acetyl-D-galactosaminyl-polypeptide | - |
? | |
UDP-N-acetyl-D-galactosamine + polypeptide | Homo sapiens | primary step in the production of mucin-type O-linked oligosaccharide groups in glycoproteins | UDP + N-acetyl-D-galactosaminyl-polypeptide | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
GalNAc-T9 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | brain-specific expression of GalNAc-T9, mRNA is most abundant in cerebellum, lower levels in cerebral cortex, frontal lobe, temporal lobe and putamen | Homo sapiens | - |
sublingual gland | GalNAc-T5 is most abundant in | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | multiple enzyme isoforms | Homo sapiens | ? | - |
? | |
additional information | GalNAc-T9 contains a 485-amino acid putative catalytic region, GalNAc-T1, -T2, -T4 and -T8 belongs to the housekeeping enzymes with ubiquitous expression, GalNAc-T3, -T5, -T6, -T7 and -T9 belongs to the tissue-specific enzymes | Homo sapiens | ? | - |
? | |
additional information | amino acid sequences of seven GalNAc-transferases | Homo sapiens | ? | - |
? | |
UDP-N-acetyl-D-galactosamine + polypeptide | - |
Homo sapiens | UDP + N-acetyl-D-galactosaminyl-polypeptide | - |
? | |
UDP-N-acetyl-D-galactosamine + polypeptide | GalNAc-T9 catalyzes O-glycosylation in brain | Homo sapiens | UDP + N-acetyl-D-galactosaminyl-polypeptide | - |
? | |
UDP-N-acetyl-D-galactosamine + polypeptide | primary step in the production of mucin-type O-linked oligosaccharide groups in glycoproteins | Homo sapiens | UDP + N-acetyl-D-galactosaminyl-polypeptide | - |
? |