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Literature summary for 2.4.1.39 extracted from

  • Collins, D.C.; Jirku, H.; Layne, D.S.
    Steroid N-acetylglucosaminyl transferase. Localization and some properties of the enzyme in rabbit tissues (1968), J. Biol. Chem., 243, 2928-2933.
    View publication on PubMed
Search for more literature for 2.4.1.39

Inhibitors

Inhibitors Comment Organism Structure
Butanol-1
-
 Oryctolagus cuniculus
diethylstilbestrol
-
 Oryctolagus cuniculus
estrone
-
 Oryctolagus cuniculus
ethanol
-
 Oryctolagus cuniculus
eugenol i.e. 2-methoxy-4-(2-propenyl)phenol Oryctolagus cuniculus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0684
-
 UDP-N-acetylglucosamine
-
 Oryctolagus cuniculus
0.168
-
 17alpha-Estradiol-3-glucuronoside
-
 Oryctolagus cuniculus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Oryctolagus cuniculus
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
17alpha-estradiol-3-glucuronoside + UDP-N-acetylglucosamine Oryctolagus cuniculus
-
 UDP + 17alpha-(N-acetyl-D-glucosaminyl)-estradiol 3-D-glucuronoside
-
 ?

Organism

Organism UniProt Comment Textmining
Oryctolagus cuniculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Oryctolagus cuniculus
-
large intestine
-
 Oryctolagus cuniculus
-
liver
-
 Oryctolagus cuniculus
-
small intestine
-
 Oryctolagus cuniculus
-

Storage Stability

Storage Stability Organism
-10°C, half-life 25 days Oryctolagus cuniculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
16,17-epiestriol-3-D-glucuronoside + UDP-N-acetylglucosamine
-
 Oryctolagus cuniculus ?
-
 ?
16-epiestriol-3-D-glucuronoside + UDP-N-acetylglucosamine
-
 Oryctolagus cuniculus UDP + 16-(N-acetyl-D-glucosaminyl)-epiestriol 3-D-glucuronoside
-
 ?
17alpha-estradiol-3-D-glucuronoside + UDP-N-acetylglucosamine
-
 Oryctolagus cuniculus UDP + 17alpha-(N-acetyl-D-glucosaminyl)-estradiol 3-D-glucuronoside
-
 ?
17alpha-estradiol-3-glucuronoside + UDP-N-acetylglucosamine
-
 Oryctolagus cuniculus UDP + 17alpha-(N-acetyl-D-glucosaminyl)-estradiol 3-D-glucuronoside
-
 ?
additional information high specificity for the 17alpha-hydroxyl group on phenolic steroids which are already attached through position 3 to glucosiduronic acid, overview Oryctolagus cuniculus ?
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
-
 Oryctolagus cuniculus