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Literature summary for 2.4.1.38 extracted from

  • Li, Z.; Wang, H.; Zong, H.; Sun, Q.; Kong, X.; Jiang, J.; Gu, J.
    Downregulation of beta1,4-galactosyltransferase 1 inhibits CDK11(p58)-mediated apoptosis induced by cycloheximide (2005), Biochem. Biophys. Res. Commun., 327, 628-636.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
ectopic expression in SMMC-7721 hepatocarcinoma cells overexpressing the CDK11(p58) kinase Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information RNAi-mediated knockdown of beta1,4-GT 1 inhibits CDK11(p58)-mediated apoptosis induced by cycloheximide, while ectopically expressed beta1,4-GT 1 increases CDK11p58-mediated apoptosis, enzyme knockout also inhibits the release of cytochrome c from mitochondria and caspase-3 processing, mechanism of beta1,4-GT 1 in CHX-induced apoptosis of CDK11p58-overexpressing cells, overview Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens downregulation of the enzyme inhibits CDK11(p58)-mediated apoptosis induced by cycloheximide, while ectopically expressed beta1,4-GT 1 increases CDK11p58-mediated apoptosis ?
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?

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information downregulation of the enzyme inhibits CDK11(p58)-mediated apoptosis induced by cycloheximide, while ectopically expressed beta1,4-GT 1 increases CDK11p58-mediated apoptosis Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
beta1,4-galactosyltransferase 1
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Homo sapiens
beta1,4-GT 1
-
Homo sapiens