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Literature summary for 2.4.1.37 extracted from

  • Johal, A.R.; Blackler, R.J.; Alfaro, J.A.; Schuman, B.; Borisova, S.; Evans, S.V.
    pH-induced conformational changes in human ABO(H) blood group glycosyltransferases confirm the importance of electrostatic interactions in the formation of the semi-closed state (2014), Glycobiology, 24, 237-246.
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
in complex with UDP and galactose, using 1% (w/v) PEG 4000, 4.5-5% (w/v) 2-methyl-2,4-pentanediol, 100 mM ammonium sulfate, 70 mM sodium chloride, 50 mM N-[2-acetamido]-2-iminodiacetic acid buffer pH 7.5, 30 mM sodium acetate buffer pH 4.6 and 5 mM MnCl2 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-alpha-D-galactose + alpha-L-fucosyl-(1,2)-D-galactosyl-R Homo sapiens
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UDP + alpha-D-galactosyl-(1,3)-[alpha-L-fucosyl(1,2)]-D-galactosyl-R
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens P16442
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-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-alpha-D-galactose + alpha-L-fucosyl-(1,2)-D-galactosyl-R
-
Homo sapiens UDP + alpha-D-galactosyl-(1,3)-[alpha-L-fucosyl(1,2)]-D-galactosyl-R
-
?

Synonyms

Synonyms Comment Organism
ABO(H) blood group B alpha-1,3-galactosyltransferase
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Homo sapiens
GTB
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Homo sapiens

pI Value

Organism Comment pI Value Maximum pI Value
Homo sapiens calculated from amino acid sequence
-
9