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Literature summary for 2.4.1.338 extracted from
- Catalytic analysis of the validamycin glycosyltransferase (ValG) and enzymatic production of 4''-epi-validamycin A (2008), J. Nat. Prod., 71, 1233-1236.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| UDP-alpha-D-glucose + validoxylamine A | Streptomyces hygroscopicus subsp. limoneus | the enzyme catalyses the ultimate step in the biosynthesis of the antifungal agent validamycin A | UDP + validamycin A | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Streptomyces hygroscopicus subsp. limoneus | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| UDP-alpha-D-glucose + validoxylamine A | the enzyme catalyses the ultimate step in the biosynthesis of the antifungal agent validamycin A | Streptomyces hygroscopicus subsp. limoneus | UDP + validamycin A | - |
? | |
| UDP-alpha-D-glucose + validoxylamine A | validoxylamine A i.e. (1S,2S,3R,6S)-4-(hydroxymethyl)-6-[[(1S,2S,3S,4R,5R)-2,3,4-trihydroxy-5-(hydroxymethyl)cyclohexyl]amino]cyclohex-4-ene-1,2,3-triol | Streptomyces hygroscopicus subsp. limoneus | UDP + validamycin A | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| valG | - |
Streptomyces hygroscopicus subsp. limoneus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| metabolism | the enzyme catalyses the ultimate step in the biosynthesis of the antifungal agent validamycin A | Streptomyces hygroscopicus subsp. limoneus |
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