Inhibitors | Comment | Organism | Structure |
---|---|---|---|
UDP-N-acetyl-5-deoxy-5-thio-alpha-D-glucosamine | effective inhibitor | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | O15294 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the enzyme is not able to transfer UDP-glucose or UDP-2-dehydro-alpha-D-glucose to peptide and protein substrates | Homo sapiens | ? | - |
? | |
UDP-N-acetyl-D-glucosamine + [protein]-L-serine | UDP-N-acetyl-5-deoxy-5-thio-alpha-D-glucosamine is a very poor (3200times slower) donor substrate compared to UDP-N-acetyl-D-glucosamine | Homo sapiens | ? | - |
? | |
UDP-N-acetyl-D-glucosamine + [protein]-L-serine | the enzyme transfers N-acetylglucosamine from the sugar donor UDP-GlcNAc onto specific serine or threonine residues of nucleocytoplasmic proteins with inversion of configuration at the anomeric center | Homo sapiens | UDP + [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
O-GlcNAc transferase | - |
Homo sapiens |
O-linked beta-N-acetylglucosamine transferase | - |
Homo sapiens |
OGT | - |
Homo sapiens |