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Literature summary for 2.4.1.255 extracted from

  • Kreppel, L.K.; Blomberg, M.A.; Hart, G.W.
    Dynamic glycosylation of nuclear and cytosolic proteins. Cloning and characterization of a unique O-GlcNAc transferase with multiple tetratricopeptide repeats (1997), J. Biol. Chem., 272, 9308-9315.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
overexpression of the Ogt gene encoding the 110 kDa alpha-subunit in Escherichia coli and transiently in HEK293 cells, DNA sequence analysis: gene Ogt is no member of a multigene family, the sequence contains multiple tandem repeats of the tetratricopeptide repeat motif Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol unlike previously described glycosyltransferases, OGT is localized to the cytosol and nucleus Rattus norvegicus 5829
-
nucleus unlike previously described glycosyltransferases, OGT is localized to the cytosol and nucleus Rattus norvegicus 5634
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
78000
-
2 * 110000 + 1 * 78000, SDS-PAGE Rattus norvegicus
110000
-
2 * 110000 + 1 * 78000, SDS-PAGE Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus P56558
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Rattus norvegicus
-
heart
-
Rattus norvegicus
-
kidney
-
Rattus norvegicus
-
liver
-
Rattus norvegicus
-
lung
-
Rattus norvegicus
-
muscle
-
Rattus norvegicus
-
ovary
-
Rattus norvegicus
-
spleen
-
Rattus norvegicus
-
thymus
-
Rattus norvegicus
-
uterus
-
Rattus norvegicus
-

Subunits

Subunits Comment Organism
heterotrimer 2 * 110000 + 1 * 78000, SDS-PAGE Rattus norvegicus

Synonyms

Synonyms Comment Organism
O-GlcNAc transferase
-
Rattus norvegicus
OGT
-
Rattus norvegicus