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Literature summary for 2.4.1.232 extracted from

  • Nakayama, K.; Nakanishi-Shindo, Y.; Tanaka, A.; Haga-Toda, Y.; Jigami, Y.
    Substrate specificity of alpha-1,6-mannosyltransferase that initiates N-linked mannose outer chain elongation in Saccharomyces cerevisiae (1997), FEBS Lett., 412, 547-550.
    View publication on PubMed
Search for more literature for 2.4.1.232

Cloned(Commentary)

Cloned (Comment) Organism
OCH1 gene encodes Och1p, an alpha-1,6-mannosyltransferase Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Saccharomyces cerevisiae Och1p is essential for the outer chain elongation of N-linked oligosaccharides ?
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 ?
additional information Saccharomyces cerevisiae Och1p Och1p is essential for the outer chain elongation of N-linked oligosaccharides ?
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 ?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
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 Och1p
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Saccharomyces cerevisiae Och1p
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 Och1p
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GDP-mannose + Man8GlcNAc2-PA best acceptor for Och1p, initiation-specific alpha-1,6-mannosyltransferase that requires the intact structure of Man8GlcNAc for efficient mannose outer chain initiation Saccharomyces cerevisiae GDP + Man9GlcNAc2-PA additional Man is attached with an alpha-1,6-linkage at the site where mannose outer chain elongation initiates ?
GDP-mannose + Man8GlcNAc2-PA best acceptor for Och1p, initiation-specific alpha-1,6-mannosyltransferase that requires the intact structure of Man8GlcNAc for efficient mannose outer chain initiation Saccharomyces cerevisiae Och1p GDP + Man9GlcNAc2-PA additional Man is attached with an alpha-1,6-linkage at the site where mannose outer chain elongation initiates ?
GDP-mannose + pyridylaminated oligosaccharide acceptor substrate specificity Saccharomyces cerevisiae ?
-
 ?
GDP-mannose + pyridylaminated oligosaccharide acceptor various high mannose-type oligosaccharides as acceptors, Man8GlcNAc2-PA is the best acceptor, the loss of 1 or 2 alpha-1,2-mannoses from Man8GlcNAc2 reduces the activity Saccharomyces cerevisiae ?
-
 ?
GDP-mannose + pyridylaminated oligosaccharide acceptor substrate specificity Saccharomyces cerevisiae Och1p ?
-
 ?
GDP-mannose + pyridylaminated oligosaccharide acceptor various high mannose-type oligosaccharides as acceptors, Man8GlcNAc2-PA is the best acceptor, the loss of 1 or 2 alpha-1,2-mannoses from Man8GlcNAc2 reduces the activity Saccharomyces cerevisiae Och1p ?
-
 ?
additional information no acceptors for Och1p: Man5GlcNAc2 completely lacking alpha-1,2-Man, Man8GlcNAcOH Saccharomyces cerevisiae ?
-
 ?
additional information Och1p is essential for the outer chain elongation of N-linked oligosaccharides Saccharomyces cerevisiae ?
-
 ?
additional information no acceptors for Och1p: Man5GlcNAc2 completely lacking alpha-1,2-Man, Man8GlcNAcOH Saccharomyces cerevisiae Och1p ?
-
 ?
additional information Och1p is essential for the outer chain elongation of N-linked oligosaccharides Saccharomyces cerevisiae Och1p ?
-
 ?