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Literature summary for 2.4.1.232 extracted from

  • Tsukahara, K.; Watanabe, T.; Yokoo, T.; Chigami, Y.
    Schizosaccharomyces pombe och1+ gene encoding alpha-1,6-mannosyltransferase and use of och1+ gene knockout fission yeast for production of glycoprteins with reduced glycosylation (2001), Jpn. Kokai Tokkyo Koho, , 11pp.
No PubMed abstract available
Search for more literature for 2.4.1.232

Cloned(Commentary)

Cloned (Comment) Organism
och1+ gene encodes alpha-1,6-mannosyltransferase, recombinant expression and cloning, och1+ gene knockout fission yeast Schizosaccharomyces pombe

Protein Variants

Protein Variants Comment Organism
additional information och1+ gene deficient strain shows loss of mannose transfer from GDP-mannose to Man9GlcNAc2-PA and loss of high-mannose type sugar chain glycosylation, och1 mutant that does not synthesize the outer chains containing mannose on acid phosphatase Schizosaccharomyces pombe

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Schizosaccharomyces pombe SpOch1p is a key enzyme of outer chain elongation of N-linked oligosaccharides ?
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 ?
additional information Schizosaccharomyces pombe Och1p SpOch1p is a key enzyme of outer chain elongation of N-linked oligosaccharides ?
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 ?

Organism

Organism UniProt Comment Textmining
Schizosaccharomyces pombe
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 Och1p
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Schizosaccharomyces pombe Och1p
-
 Och1p
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GDP-mannose + Man9GlcNAc2-PA enzyme incorporates alpha-1,6-linked mannose into the substrate Schizosaccharomyces pombe GDP + Man10GlcNAc2-PA
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 ?
GDP-mannose + Man9GlcNAc2-PA enzyme incorporates alpha-1,6-linked mannose into the substrate Schizosaccharomyces pombe Och1p GDP + Man10GlcNAc2-PA
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 ?
GDP-mannose + pyridylaminated oligosaccharide acceptor substrate specificity Schizosaccharomyces pombe ?
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 ?
GDP-mannose + pyridylaminated oligosaccharide acceptor SpOch1p Schizosaccharomyces pombe ?
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 ?
GDP-mannose + pyridylaminated oligosaccharide acceptor substrate specificity Schizosaccharomyces pombe Och1p ?
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 ?
GDP-mannose + pyridylaminated oligosaccharide acceptor SpOch1p Schizosaccharomyces pombe Och1p ?
-
 ?
additional information SpOch1p is a key enzyme of outer chain elongation of N-linked oligosaccharides Schizosaccharomyces pombe ?
-
 ?
additional information SpOch1p is a key enzyme of outer chain elongation of N-linked oligosaccharides Schizosaccharomyces pombe Och1p ?
-
 ?