Organism | UniProt | Comment | Textmining |
---|---|---|---|
Danio rerio | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
epithelial cell | Lfng is required cell autonomously in neural epithelial cells to limit the amount of neurogenesis and to maintain progenitors | Danio rerio | - |
hindbrain | isoform lunatic fringe Lfng is expressed by progenitors in neurogenic regions and downregulated in cells that have initiated neuronal differentiation | Danio rerio | - |
Synonyms | Comment | Organism |
---|---|---|
LFNG | - |
Danio rerio |
Organism | Comment | Expression |
---|---|---|
Danio rerio | the expression of Lfng does not require Notch activity, but rather is regulated downstream of proneural genes that are widely expressed by neural progenitors | additional information |
General Information | Comment | Organism |
---|---|---|
physiological function | Lfng is required cell autonomously in neural epithelial cells to limit the amount of neurogenesis and to maintain progenitors. Lfng is not required for the role of Notch in interneuronal fate choice, which is mediated by Notch1a. The expression of Lfng does not require Notch activity, but rather is regulated downstream of proneural genes that are widely expressed by neural progenitors | Danio rerio |