Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | fringe requires a properly folded EGF repeat modified by O-fucose for its enzymatic activity | Drosophila melanogaster | |
additional information | fringe requires a properly folded EGF repeat modified by O-fucose for its enzymatic activity | Mammalia | |
additional information | fringe requires a properly folded EGF repeat modified by O-fucose for its enzymatic activity | Homo sapiens |
Application | Comment | Organism |
---|---|---|
medicine | the Notch signaling pathway is involved in numerous developmental cascades in mammals, mutations in the pathway have been implicated in a variety of Human diseases, like CADASIL, spondylocostal dysostosis, alagille syndrome, cancer and multiple sclerosis | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
- |
Mammalia |
Crystallization (Comment) | Organism |
---|---|
- |
Mammalia |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
Golgi apparatus | - |
Drosophila melanogaster | 5794 | - |
Golgi apparatus | - |
Mammalia | 5794 | - |
Golgi apparatus | - |
Homo sapiens | 5794 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mn2+ | - |
Drosophila melanogaster | |
Mn2+ | - |
Mammalia | |
Mn2+ | - |
Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Drosophila melanogaster | transfers a beta-D-GlcNAc residue from UDP-D-GlcNAc to the fucose residue of a fucosylated protein acceptor | ? | - |
? | |
additional information | Mammalia | transfers a beta-D-GlcNAc residue from UDP-D-GlcNAc to the fucose residue of a fucosylated protein acceptor | ? | - |
? | |
additional information | Homo sapiens | transfers a beta-D-GlcNAc residue from UDP-D-GlcNAc to the fucose residue of a fucosylated protein acceptor | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Drosophila melanogaster | - |
- |
- |
Homo sapiens | - |
- |
- |
Mammalia | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Mammalia |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
eye | - |
Drosophila melanogaster | - |
leg | - |
Drosophila melanogaster | - |
oocyte | - |
Drosophila melanogaster | - |
wing | - |
Drosophila melanogaster | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | transfers a beta-D-GlcNAc residue from UDP-D-GlcNAc to the fucose residue of a fucosylated protein acceptor | Drosophila melanogaster | ? | - |
? | |
additional information | transfers a beta-D-GlcNAc residue from UDP-D-GlcNAc to the fucose residue of a fucosylated protein acceptor | Mammalia | ? | - |
? | |
additional information | transfers a beta-D-GlcNAc residue from UDP-D-GlcNAc to the fucose residue of a fucosylated protein acceptor | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
beta-1,3-N-acetylglucosaminyltransferase | - |
Drosophila melanogaster |
beta-1,3-N-acetylglucosaminyltransferase | - |
Mammalia |
beta-1,3-N-acetylglucosaminyltransferase | - |
Homo sapiens |
Dfng | - |
Drosophila melanogaster |