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Literature summary for 2.4.1.22 extracted from

  • Fujita-Yamaguchi, Y.; Yoshida, A.
    Purification and characterization of human serum galactosyltransferase (lactose synthetase A protein) (1981), J. Biol. Chem., 256, 2701-2706.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
alpha-lactalbumin alters the acceptor specificity of the galactosyltransferase and thereby increases lactose synthesis and decreases N-acetylglucosamine synthesis Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4
-
glucose
-
Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Mn2+ required, Km: 0.2 mM Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein galactosyl transferase component contains 11% carbohydrate Homo sapiens

Purification (Commentary)

Purification (Comment) Organism
galactosyl transferase component Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
blood serum
-
Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDPgalactose + D-glucose
-
Homo sapiens lactose + UDP
-
?

Subunits

Subunits Comment Organism
More galactosyl transferase component has a MW of 49000 Da, SDS-PAGE Homo sapiens