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Literature summary for 2.4.1.214 extracted from

  • Zisoulis, D.G.; Kansas, G.S.
    H-Ras and phosphoinositide 3-kinase cooperate to induce alpha(1,3)-fucosyltransferase VII expression in Jurkat T cells (2004), J. Biol. Chem., 279, 39495-39504.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information H-Ras and phosphoinositide 3-kinase cooperate to induce alpha(1,3)-fucosyltransferase VII expression in Jurkat T cellsvia the Raf-MEK-ERK pathway, but induction of FucT-VII requires the concomitant activation of at least 3 different signaling pathways, overview Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens FucT-VII is essential for biosynthesis of selectin binding ligands in T-cells, H-Ras and phosphoinositide 3-kinase cooperate to induce alpha(1,3)-fucosyltransferase VII expression in Jurkat T cells via the Raf-MEK-ERK pathway, but induction of FucT-VII requires the concomitant activation of at least 3 different signaling pathways, overview ?
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Organism

Organism UniProt Comment Textmining
Homo sapiens
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Source Tissue

Source Tissue Comment Organism Textmining
JURKAT cell mechanism of FucT-VII induction, overview Homo sapiens
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lymphocyte
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Homo sapiens
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T-cell
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Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information FucT-VII is essential for biosynthesis of selectin binding ligands in T-cells, H-Ras and phosphoinositide 3-kinase cooperate to induce alpha(1,3)-fucosyltransferase VII expression in Jurkat T cells via the Raf-MEK-ERK pathway, but induction of FucT-VII requires the concomitant activation of at least 3 different signaling pathways, overview Homo sapiens ?
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Synonyms

Synonyms Comment Organism
alpha(1,3)-fucosyltransferase VII
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Homo sapiens
FucT-VII
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Homo sapiens