Literature summary for 2.4.1.214 extracted from

Wang, Q.Y.; Guo, P.; Duan, L.L.; Shen, Z.H.; Chen, H.L.
alpha-1,3-Fucosyltransferase-VII stimulates the growth of hepatocarcinoma cells via the cyclin-dependent kinase inhibitor p27Kip1 (2005), Cell. Mol. Life Sci., 62, 171-178.

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Cloned(Commentary)

Cloned (Comment)	Organism
expression of FucT-VII in H7721 hepatocarcinoma cells	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Homo sapiens	alpha1,3-fucosylation by FucT-VII is a step in the biosynthesis of Lewis X antigen, FucT-VII stimulates the growth of hepatocarcinoma cells via the cyclin-dependent kinase inhibitor p27Kip1, phosphorylation of the Rb protein is involved, signaling pathway overview	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	FucT-VII	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	alpha1,3-fucosylation by FucT-VII is a step in the biosynthesis of Lewis X antigen, FucT-VII stimulates the growth of hepatocarcinoma cells via the cyclin-dependent kinase inhibitor p27Kip1, phosphorylation of the Rb protein is involved, signaling pathway overview	Homo sapiens	?	-	?

Synonyms

Synonyms	Comment	Organism
alpha-1,3-fucosyltransferase-VII	-	Homo sapiens
FucT-VII	-	Homo sapiens

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Release 2023.1 (January 2023)