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BRENDA support

Literature summary for 2.4.1.212 extracted from

  • Berdiaki, A.; Nikitovic, D.; Tsatsakis, A.; Katonis, P.; Karamanos, N.K.; Tzanakakis, G.N.
    bFGF induces changes in hyaluronan synthase and hyaluronidase isoform expression and modulates the migration capacity of fibrosarcoma cells (2009), Biochim. Biophys. Acta, 1790, 1258-1265.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens Q92839 isoform HAS1
-

Source Tissue

Source Tissue Comment Organism Textmining
HT-1080 cell
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Homo sapiens
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Expression

Organism Comment Expression
Homo sapiens basic fibroblast growth factor bFGF increases HA-synthase-1 and -2 expression and enhances high molecular weight hyaluronan deposition in the pericellular matrix up

General Information

General Information Comment Organism
physiological function mainly high molecular weight hyaluronan synthesized by isoform HAS1 regulates HT-1080 cell motility Homo sapiens