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Literature summary for 2.4.1.212 extracted from
- Recombinant synthesis of hyaluronan by Agrobacterium sp (2007), Biotechnol. Prog., 23, 1038-1042.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| the Escherichia coli expression vector pQE80L and the broad host range cloning vector pBBR122 are used | Pasteurella multocida |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| UDP-alpha-D-glucuronate + N-acetyl-beta-D-glucosaminyl-(1-4)-beta-D-glucuronosyl-(1-3)-[nascent hyaluronan] | Pasteurella multocida | - |
UDP + beta-D-glucuronosyl-(1-3)-N-acetyl-beta-D-glucosaminyl-(1-4)-beta-D-glucuronosyl-(1-3)-[nascent hyaluronan] | - |
? |  |
| UDP-alpha-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1-3)-N-acetyl-beta-D-glucosaminyl-(1-4)-[nascent hyaluronan] | Pasteurella multocida | - |
UDP + N-acetyl-beta-D-glucosaminyl-(1-4)-beta-D-glucuronosyl-(1-3)-N-acetyl-beta-D-glucosaminyl-(1-4)-[nascent hyaluronan] | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Pasteurella multocida | Q7BLV3 | - |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| recombinant synthesis of hyaluronan is carried out with Agrobacterium sp. strain ATCC 31749, hyaluronan is primarly found in the culture medium | Pasteurella multocida |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| UDP-alpha-D-glucuronate + N-acetyl-beta-D-glucosaminyl-(1-4)-beta-D-glucuronosyl-(1-3)-[nascent hyaluronan] | - |
Pasteurella multocida | UDP + beta-D-glucuronosyl-(1-3)-N-acetyl-beta-D-glucosaminyl-(1-4)-beta-D-glucuronosyl-(1-3)-[nascent hyaluronan] | - |
? | |
| UDP-alpha-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1-3)-N-acetyl-beta-D-glucosaminyl-(1-4)-[nascent hyaluronan] | - |
Pasteurella multocida | UDP + N-acetyl-beta-D-glucosaminyl-(1-4)-beta-D-glucuronosyl-(1-3)-N-acetyl-beta-D-glucosaminyl-(1-4)-[nascent hyaluronan] | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| HAS | - |
Pasteurella multocida |
| hyaluronan synthase | - |
Pasteurella multocida |
| PmHAS | - |
Pasteurella multocida |
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Release 2023.1 (January 2023)
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