Literature summary for 2.4.1.20 extracted from

Chomvong, K.; Lin, E.; Blaisse, M.; Gillespie, A.E.; Cate, J.H.
Relief of xylose binding to cellobiose phosphorylase by a single distal mutation (2017), ACS Synth. Biol., 6, 206-210 .

Search for more literature for 2.4.1.20

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Saccharomyces cerevisiae strain D452-2	Saccharophagus degradans

Protein Variants

Protein Variants	Comment	Organism
Y47H	the mutation is responsible for improved cellobiose consumption in the presence of xylose. The mutation alters the conformation of the enzyme dimer complex to reduce xylose binding to the active site	Saccharophagus degradans
Y47H/K256/E270D/I384L/N488D/N578S/Y631F	the mutant strain shows improved growth and cellobiose consumption in comparison to the strain expressing wild type enzyme	Saccharophagus degradans

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
cellobiose + phosphate	Saccharophagus degradans	-	alpha-D-glucose 1-phosphate + D-glucose	-	?

Organism

Organism	UniProt	Comment	Textmining
Saccharophagus degradans	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
cellobiose + phosphate	-	Saccharophagus degradans	alpha-D-glucose 1-phosphate + D-glucose	-	?

Synonyms

Synonyms	Comment	Organism
Cbp	-	Saccharophagus degradans

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Release 2023.1 (January 2023)