Inhibitors | Comment | Organism | Structure |
---|---|---|---|
4-deoxy-D-glucose | competitive with D-glucose, dead end inhibitor | Cellulomonas uda | |
4-thio-cellobiose | weak inhibition in both directions of reaction | Cellulomonas uda | |
cellobiose | substrate inhibition, competitive with glucose-1-phosphate | Cellulomonas uda | |
D-glucose | mixed type inhibition against cellobiose, pure beta-D-glucose inhibits stronger than mixture of both anomers | Cellulomonas uda | |
D-glucose 1-phosphate | substrate inhibition, competitive with cellobiose | Cellulomonas uda |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
1.2 | - |
phosphate | - |
Cellulomonas uda | |
2.15 | - |
alpha-D-glucose 1-phosphate | - |
Cellulomonas uda | |
2.26 | - |
D-glucose | - |
Cellulomonas uda | |
4.3 | - |
cellobiose | - |
Cellulomonas uda | |
7.4 | - |
6-deoxy-6-fluoro-D-glucose | - |
Cellulomonas uda | |
10.2 | - |
6-deoxy-D-glucose | - |
Cellulomonas uda | |
10.8 | - |
D-glucoseamine | - |
Cellulomonas uda | |
15.9 | - |
D-xylose | - |
Cellulomonas uda | |
17.2 | - |
2-deoxy-2-fluoro-D-glucose | - |
Cellulomonas uda | |
24.3 | - |
2-deoxy-D-glucose | - |
Cellulomonas uda | |
27.3 | - |
D-mannose | - |
Cellulomonas uda |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
cellobiose + phosphate | Cellulomonas uda | important for energy efficient catabolism of cellobiose in cytoplasm | alpha-D-glucose 1-phosphate + D-glucose | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Cellulomonas uda | - |
- |
- |
Cellulomonas uda | - |
DSM 20108 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
alpha-D -glucose 1-fluoride + D-glucose | - |
Cellulomonas uda | cellobiose + fluoride | - |
ir | |
alpha-D-glucose 1-phosphate + 2-deoxy-2-fluoro-D-glucose | - |
Cellulomonas uda | ? | - |
? | |
alpha-D-glucose 1-phosphate + 2-deoxy-D-glucose | - |
Cellulomonas uda | ? | - |
? | |
alpha-D-glucose 1-phosphate + 6-deoxy-6-fluoro-D-glucose | - |
Cellulomonas uda | ? | - |
? | |
alpha-D-glucose 1-phosphate + 6-deoxy-D-glucose | - |
Cellulomonas uda | ? | - |
? | |
alpha-D-glucose 1-phosphate + D-glucosamine | - |
Cellulomonas uda | ? | - |
? | |
alpha-D-glucose 1-phosphate + D-glucose | - |
Cellulomonas uda | cellobiose + phosphate | - |
? | |
alpha-D-glucose 1-phosphate + D-mannose | - |
Cellulomonas uda | ? | - |
? | |
alpha-D-glucose 1-phosphate + D-xylose | - |
Cellulomonas uda | ? | - |
? | |
beta-D-glucose 1-phosphate + alpha-D-glucopyranosyl fluoride | beta-D-glucopyranosyl fluoride is not ulilized | Cellulomonas uda | beta-cellobiose + HF | - |
? | |
cellobiose + arsenate | - |
Cellulomonas uda | D-glucose + alpha-D-glucose 1-arsenate | alpha-D-glucose 1-arsenate hydrolyses spontaneously to form D-glucose and arsenate | ir | |
cellobiose + phosphate | beta-cellobiose preferred over alpha-anomer | Cellulomonas uda | alpha-D-glucose 1-phosphate + D-glucose | - |
? | |
cellobiose + phosphate | ternary-complex kinetic mechanism | Cellulomonas uda | alpha-D-glucose 1-phosphate + D-glucose | - |
? | |
cellobiose + phosphate | important for energy efficient catabolism of cellobiose in cytoplasm | Cellulomonas uda | alpha-D-glucose 1-phosphate + D-glucose | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CuCbP | - |
Cellulomonas uda |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
5.6 | - |
D-glucoseamine | - |
Cellulomonas uda | |
6.6 | - |
D-mannose | - |
Cellulomonas uda | |
8 | - |
2-deoxy-2-fluoro-D-glucose | - |
Cellulomonas uda | |
8.7 | - |
D-xylose | - |
Cellulomonas uda | |
11.6 | - |
2-deoxy-D-glucose | - |
Cellulomonas uda | |
29.1 | - |
cellobiose | - |
Cellulomonas uda | |
43.2 | - |
D-glucose | - |
Cellulomonas uda | |
44.6 | - |
6-deoxy-6-fluoro-D-glucose | - |
Cellulomonas uda | |
55.3 | - |
6-deoxy-D-glucose | - |
Cellulomonas uda |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
2.2 | - |
D-glucose | - |
Cellulomonas uda | |
3.2 | - |
D-glucose 1-phosphate | - |
Cellulomonas uda | |
4.4 | - |
4-deoxy-D-glucose | - |
Cellulomonas uda | |
13 | - |
4-thio-cellobiose | in presence of saturating concentrations of phosphate | Cellulomonas uda | |
14.8 | - |
cellobiose | - |
Cellulomonas uda |