Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Homo sapiens | 16020 | - |
microsome | - |
Homo sapiens | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | enzyme defect in paroxysmal nocturnal hemoglobinuria | ? | - |
? | |
UDP-N-acetyl-D-glucosamine + phosphatidylinositol | Homo sapiens | involved in the first step of glycosylphosphatidylinositol, i.e. GPI, membrane anchor formation of surface glycoproteins | UDP + N-acetyl-D-glucosaminyl-phosphatidylinositol | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
lymphoblastoid cell line | with paroxysmal nocturnal hemoglobinuria phenotype, i.e. PNH, obtained by Epstein-Barr immortalization of lymphocytes from PNH-patients | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | enzyme defect in paroxysmal nocturnal hemoglobinuria | Homo sapiens | ? | - |
? | |
UDP-N-acetyl-D-glucosamine + phosphatidylinositol | - |
Homo sapiens | UDP + N-acetyl-D-glucosaminyl-phosphatidylinositol | in alpha1-6 linkage | ? | |
UDP-N-acetyl-D-glucosamine + phosphatidylinositol | involved in the first step of glycosylphosphatidylinositol, i.e. GPI, membrane anchor formation of surface glycoproteins | Homo sapiens | UDP + N-acetyl-D-glucosaminyl-phosphatidylinositol | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
assay at | Homo sapiens |