Literature summary for 2.4.1.186 extracted from

Pitcher, J.; Smythe, C.; Campell, D.G.; Cohen, P.
Identification of the 38-kDa subunit of rabbit skeletal muscle glycogen synthase as glycogenin (1987), Eur. J. Biochem., 169, 497-502.

Search for more literature for 2.4.1.186

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
38000	-	gel filtration, SDS-PAGE, glycogenin glucosyltransferase represents the smaller subunit of glycogen synthase	Oryctolagus cuniculus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
UDP-glucose + glycogenin	Oryctolagus cuniculus	the glycogenin subunit of glycogen synthase, EC 2.4.1.11, catalyzes this reaction, i.e. the enzyme catalyzes its own glucosylation	UDP + glucosylated glycogenin	-	?

Organism

Organism	UniProt	Comment	Textmining
Oryctolagus cuniculus	-	-	-

Posttranslational Modification

Posttranslational Modification	Comment	Organism
glycoprotein	autoglycosylation	Oryctolagus cuniculus

Purification (Commentary)

Purification (Comment)	Organism
separation from glycogen synthase, EC 2.4.1.11, by LiBr	Oryctolagus cuniculus

Source Tissue

Source Tissue	Comment	Organism	Textmining
skeletal muscle	-	Oryctolagus cuniculus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
UDP-glucose + glycogenin	autoglycosylation reaction	Oryctolagus cuniculus	UDP + glucosylated glycogenin	-	?
UDP-glucose + glycogenin	the glycogenin subunit of glycogen synthase, EC 2.4.1.11, catalyzes this reaction, i.e. the enzyme catalyzes its own glucosylation	Oryctolagus cuniculus	UDP + glucosylated glycogenin	-	?

Subunits

Subunits	Comment	Organism
More	glycogenin glucosyltransferase, MW 38 kDa, represents the smaller subunit of glycogen synthase, both enzyme form a heterodimeric complex of molar ratio 1:1	Oryctolagus cuniculus
More	purified glycogenin associates as a dimer in absence of SDS, MW 64 kDa, glycerol density gradient centrifugation	Oryctolagus cuniculus

Temperature Optimum [°C]

Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
30	-	assay at	Oryctolagus cuniculus

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
7	-	assay at	Oryctolagus cuniculus

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Release 2023.1 (January 2023)