Inhibitors | Comment | Organism | Structure |
---|---|---|---|
silibinin-glucuronide | cmpetitive; competitive | Rattus norvegicus | |
silymarin | competitive | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Rattus norvegicus | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | Q64550 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-glucuronate + p-nitrophenol | - |
Rattus norvegicus | UDP + 4-nitrophenyl-alpha-D-glucuronide | - |
? | |
UDPglucuronate + bilirubin | - |
Rattus norvegicus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
bilirubin-specific UDPGT isozyme 1 | - |
Rattus norvegicus |
HUG-BR1 | - |
Rattus norvegicus |
phenol-metabolizing UDP-glucuronosyltransferase | - |
Rattus norvegicus |
UDP-glucuronosyltransferase 1A1 | - |
Rattus norvegicus |
UDP-glucuronosyltransferase 1A6 | - |
Rattus norvegicus |
UDPGT | - |
Rattus norvegicus |
UGT-1A | - |
Rattus norvegicus |
UGT-1F | - |
Rattus norvegicus |
UGT1-01 | - |
Rattus norvegicus |
UGT1-06 | - |
Rattus norvegicus |
UGT1.1 | - |
Rattus norvegicus |
UGT1.6 | - |
Rattus norvegicus |
UGT1A | - |
Rattus norvegicus |
UGT1A1 | - |
Rattus norvegicus |
UGT1A6 | - |
Rattus norvegicus |
UGT1F | - |
Rattus norvegicus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | Ki-value for silibinin-glucuronide at 37°C, pH 7.8 is 0.016 mg/ml | Rattus norvegicus | |
additional information | - |
additional information | Ki-value for silibinin-glucuronide at 37°C, pH 8.0 is 0.014 mg/m. Ki-value for silymarin at 37°C, pH 8.0 is 0.051 mg/ml | Rattus norvegicus |