Cloned (Comment) | Organism |
---|---|
expression of theUGT 1 locus in transgenic mice provides only a unique opportunity to examine the regulatory properties that control the tissue-specific and xenobiotic receptor-elicited expression patterns of the individual UGT1A genes and also enriches an understanding of how the UGT1 locus may be regulated at times where changes are apparent in the physiological levels of circulating hormones | Homo sapiens |
expression of theUGT1 locus in transgenic mice provides only a unique opportunity to examine the regulatory properties that control the tissue-specific and xenobiotic receptor-elicited expression patterns of the individual UGT1A genes and also enriches an understanding of how the UGT1 locus may be regulated at times where changes are apparent in the physiological levels of circulating hormones | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P19224 | - |
- |
Homo sapiens | P22309 | - |
- |
Homo sapiens | P22310 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | of trangenic mice expressing the UGT1 locus of human. In maternal 14-day post-conception Tg-UGT1 mice, liver UGT1A1, UGT1A4, and UGT1A6 are induced, with the levels returning to near normal by birth. However, maternal liver UGT1A4 and UGT1A6 are dramatically elevated and maintained after birth, indicating that these proteins may play a critical role in maternal metabolism during lactation | Homo sapiens | - |
liver | of transgenic mice expressing the UGT1 locus of human. In maternal 14-day post-conception Tg-UGT1 mice, liver UGT1A1, UGT1A4, and UGT1A6 are induced, with the levels returning to near normal by birth. However, maternal liver UGT1A4 and UGT1A6 are dramatically elevated and maintained after birth, indicating that these proteins may play a critical role in maternal metabolism during lactation | Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
UGT1A1 | - |
Homo sapiens |
UGT1A4 | - |
Homo sapiens |
UGT1A6 | - |
Homo sapiens |