Inhibitors | Comment | Organism | Structure |
---|---|---|---|
estradiol | - |
Sus scrofa | |
estrone | competitive to estradiol-17beta | Sus scrofa |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | - |
Sus scrofa | |
0.046 | - |
estradiol-17beta | range between 0.045 mM and 0.047 mM | Sus scrofa | |
0.22 | - |
UDPglucuronic acid | - |
Sus scrofa |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Sus scrofa | - |
- |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
52000 | - |
UGT2B7 | Sus scrofa |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
pig | - |
Purification (Comment) | Organism |
---|---|
- |
Sus scrofa |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
small intestine | - |
Sus scrofa | - |
Storage Stability | Organism |
---|---|
-20°C, stable | Sus scrofa |
0°C, 14 days, 80% loss of activity | Sus scrofa |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
estradiol-17alpha + UDPglucuronate | - |
Sus scrofa | UDP + 17-alpha-estradiol O-glucuronide | - |
? | |
estradiol-17beta + UDPglucuronate | - |
Sus scrofa | estradiol-17beta-3-monoglucuronide + UDP | - |
? | |
estriol + UDPglucuronate | - |
Sus scrofa | UDP + estriol-16 alpha-glucuronide | - |
? | |
estrone + UDPglucuronate | - |
Sus scrofa | UDP + estrone 3-O-glucuronide | - |
? |
Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
---|---|---|---|
50 | - |
increase of activity up to 50°C, half-life at 50°C: 15 min | Sus scrofa |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
stable up to | Sus scrofa |
50 | - |
half-life 15 min | Sus scrofa |
62 | - |
complete inactivation | Sus scrofa |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | - |
estradiol-17-beta, Tris/maleate or phosphate buffer | Sus scrofa |
7.6 | - |
estradiol-17beta as substrate, Tris/HCl buffer | Sus scrofa |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.005 | - |
estradiol | - |
Sus scrofa |