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Literature summary for 2.4.1.17 extracted from

  • Falany, C.N.; Green, M.D.; Swain, E.; Tephly, T.R.
    Substrate specificity and characterization of rat liver p-nitrophenol, 3alpha-hydroxysteroid and 17beta-hydroxysteroid UDP-glucuronosyltransferases (1986), Biochem. J., 238, 65-73.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.4.1.17

Activating Compound

Activating Compound Comment Organism Structure
phosphatidylcholine required by purified preparations for optimal activity Rattus norvegicus
Phospholipids effect of various phospholipids Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Rattus norvegicus
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
50000
-
 x * 50000, 17beta-hydroxysteroid UDP-glucuronyltransferase Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 Sprague-Dawley rat
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
17beta-hydroxy-5alpha-androstan-3-one + UDPglucuronate
-
 Rattus norvegicus UDP + 17beta-hydroxy-5alpha-androstan-3-one 17O-glucuronide
-
 ?
4-nitrophenol + UDP-glucuronate
-
 Rattus norvegicus 4-nitrophenyl beta-D-glucuronide + UDP
-
 ?
chenodeoxycholic acid + UDP-glucuronate
-
 Rattus norvegicus UDP + ?
-
 ?
etiocholanone + UDPglucuronate
-
 Rattus norvegicus UDP + etiocholanone O-glucuronide
-
 ?
lithocholic acid + UDPglucuronate
-
 Rattus norvegicus UDP + ?
-
 ?
testosterone + UDPglucuronate
-
 Rattus norvegicus UDP + testosterone O-glucuronide
-
 ?

Subunits

Subunits Comment Organism
? 4-nitrophenol UDP-glucuronyltransferase Rattus norvegicus
? 3alpha-hydroxysteroid UDP-glucuronyltransferase Rattus norvegicus
? all values determined by SDS-PAGE Rattus norvegicus
? x * 50000, 17beta-hydroxysteroid UDP-glucuronyltransferase Rattus norvegicus