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Literature summary for 2.4.1.17 extracted from

  • Yokota, H.; Yuasa, A.; Sato, R.
    Purification and properties of a form of UDP-glucuronyltransferase from liver microsomes of 3-methylcholanthrene-treated rats (1988), J. Biochem., 104, 531-536.
    View publication on PubMed
Search for more literature for 2.4.1.17

Activating Compound

Activating Compound Comment Organism Structure
phosphatidylcholine required by purified preparations for optimal activity Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Rattus norvegicus
-
-

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 Wistar strain
-
Rattus norvegicus Wistar
-
 Wistar strain
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein mannose-type oligosaccharide chains Rattus norvegicus

Purification (Commentary)

Purification (Comment) Organism
-
 Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.092
-
 4-hydroxybiphenyl as substrate, enzyme induced by 3-methylcholanthrene Rattus norvegicus
1.7
-
 5-hydroxytryptamine, enzyme induced by 3-methylcholanthrene Rattus norvegicus
1.8
-
 eugenol as substrate, enzyme induced by 3-methylcholanthrene Rattus norvegicus
4
-
 1-naphthol as substrate, Wistar strain treated with 3-methylcholanthrene Rattus norvegicus
5
-
 4-nitrophenol as substrate, Wistar strain treated with 3-methylcholanthrene Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-naphthol + UDP-glucuronate
-
 Rattus norvegicus naphth-1-yl-beta-D-glucuronide + UDP
-
 ?
1-naphthol + UDP-glucuronate
-
 Rattus norvegicus Wistar naphth-1-yl-beta-D-glucuronide + UDP
-
 ?
2-methoxy-4-(2-propenyl)phenol + UDPglucuronate i.e. eugenol Rattus norvegicus UDP + 2-methoxy-4-(2-propenyl)phenylglucuronide
-
 ?
4-hydroxybiphenyl + UDP-glucuronate
-
 Rattus norvegicus UDP + 4-hydroxybiphenyl 4-O-beta-D-glucuronide
-
 ?
4-hydroxybiphenyl + UDP-glucuronate
-
 Rattus norvegicus Wistar UDP + 4-hydroxybiphenyl 4-O-beta-D-glucuronide
-
 ?
4-nitrophenol + UDP-glucuronate
-
 Rattus norvegicus 4-nitrophenyl beta-D-glucuronide + UDP
-
 ?
4-nitrophenol + UDP-glucuronate
-
 Rattus norvegicus Wistar 4-nitrophenyl beta-D-glucuronide + UDP
-
 ?
bilirubin + UDPglucuronate no activity Rattus norvegicus bilirubin monoglucuronoside + bilirubin diglucuronoside + UDP
-
 ?
bilirubin + UDPglucuronate no activity Rattus norvegicus Wistar bilirubin monoglucuronoside + bilirubin diglucuronoside + UDP
-
 ?
serotonin + UDPglucuronate
-
 Rattus norvegicus tryptamine 5-O-beta-D-glucuronide + UDP
-
 ?
testosterone + UDPglucuronate no activity Rattus norvegicus UDP + testosterone O-glucuronide
-
 ?
testosterone + UDPglucuronate no activity Rattus norvegicus Wistar UDP + testosterone O-glucuronide
-
 ?

Subunits

Subunits Comment Organism
? all values determined by SDS-PAGE Rattus norvegicus