Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Nikkomycin | 0.015 for chitin synthetase III; IC50: 0.022 mM for chitin synthetase II; IC50: 0.032 mM for chitin synthetase I | Kluyveromyces bulgaricus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0133 | - |
6-O-dansyl-N-acetylglucosamine | chitin synthetase I | Kluyveromyces bulgaricus | |
0.2 | - |
6-O-dansyl-N-acetylglucosamine | chitin synthetase III | Kluyveromyces bulgaricus | |
0.5 | - |
6-O-dansyl N-acetylglucosamine | chitin synthetase II | Kluyveromyces bulgaricus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Kluyveromyces bulgaricus | - |
ATCC 96631 | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.0025 | - |
chitin synthetase III, activity at the end of exponential growth phase | Kluyveromyces bulgaricus |
0.0028 | - |
chitin synthetase II, activity at the end of exponential growth phase | Kluyveromyces bulgaricus |
0.008 | - |
chitin synthetase I, activity at the end of exponential growth phase | Kluyveromyces bulgaricus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
6-O-dansyl-N-acetylglucosamine + [1,4-(N-acetyl-beta-D-glucosaminyl)]n | - |
Kluyveromyces bulgaricus | ? | - |
? | |
acetyl-D-glucosamine + [1,4-(N-acetyl-beta-D-glucosaminyl)]n | - |
Kluyveromyces bulgaricus | UDP + [1,4-(N-acetyl-beta-D-glucosaminyl)]n+1 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
chitin synthetase I | - |
Kluyveromyces bulgaricus |
chitin synthetase II | - |
Kluyveromyces bulgaricus |
chitin synthetase III | - |
Kluyveromyces bulgaricus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.022 | - |
IC50: 0.022 mM for chitin synthetase II | Kluyveromyces bulgaricus | Nikkomycin | |
0.032 | - |
IC50: 0.032 mM for chitin synthetase I | Kluyveromyces bulgaricus | Nikkomycin |