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Literature summary for 2.4.1.16 extracted from
- A comparative study of properties of chitin synthase from two Mortierella species (1985), Can. J. Microbiol., 31, 1035-1040.
No PubMed abstract available
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| GlcNAc | stimulates | Mortierella pusilla |  |
| GlcNAc | stimulates | Mortierella candelabrum | |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Polyoxin D | - |
Mortierella candelabrum | |
| Polyoxin D | - |
Mortierella pusilla | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 1.8 | - |
UDP-GlcNAc | - |
Mortierella pusilla | |
| 2 | - |
UDP-GlcNAc | - |
Mortierella candelabrum | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| additional information | - |
Mortierella pusilla | - |
- |
| additional information | - |
Mortierella candelabrum | - |
- |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | slight increase in activity | Mortierella pusilla | |
| Ca2+ | slight increase in activity | Mortierella candelabrum | |
| Co2+ | stimulates | Mortierella pusilla | |
| Co2+ | stimulates | Mortierella candelabrum | |
| Mg2+ | stimulates | Mortierella pusilla | |
| Mg2+ | stimulates | Mortierella candelabrum | |
| Mn2+ | slight stimulation | Mortierella pusilla | |
| Mn2+ | slight stimulation | Mortierella candelabrum | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mortierella candelabrum | - |
- |
- |
| Mortierella pusilla | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| proteolytic modification | moderate degree of activation by trypsin | Mortierella pusilla |
| proteolytic modification | moderate degree of activation by trypsin | Mortierella candelabrum |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| mycelium | - |
Mortierella pusilla | - |
| mycelium | - |
Mortierella candelabrum | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| UDP-N-acetyl-D-glucosamine + [1,4-(N-acetyl-beta-D-glucosaminyl)]n | - |
Mortierella pusilla | UDP + [1,4-(N-acetyl-beta-D-glucosaminyl)]n+1 | - |
? | |
| UDP-N-acetyl-D-glucosamine + [1,4-(N-acetyl-beta-D-glucosaminyl)]n | - |
Mortierella candelabrum | UDP + [1,4-(N-acetyl-beta-D-glucosaminyl)]n+1 | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 28 | - |
- |
Mortierella pusilla |
| 30 | - |
- |
Mortierella pusilla |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Mortierella candelabrum |
| additional information | - |
activity increases during low temperature storage | Mortierella pusilla |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6 | - |
- |
Mortierella pusilla |
| 6.2 | - |
- |
Mortierella candelabrum |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0058 | - |
Polyoxin D | - |
Mortierella candelabrum | |
| 0.0069 | - |
Polyoxin D | - |
Mortierella pusilla | |
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