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Literature summary for 2.4.1.155 extracted from

  • Dawson, G.; Moskal, J.R.; Dawson, S.A.
    Transfection of 2,6 and 2,3-sialyltransferase genes and GlcNAc-transferase genes into human glioma cell line U-373 MG affects glycoconjugate expression and enhances cell death (2004), J. Neurochem., 89, 1436-1444.
    View publication on PubMed
Search for more literature for 2.4.1.155

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.28
-
 GlcNAc-beta(1-2)Man-alpha(1-3)(GlcNAc-beta(1-2)Man-alpha(1-4))Man-beta(1-4)GlcNAc-2-amino pyridine Hep2G cell, pH 7.0, 37°C Homo sapiens
2.4
-
 GlcNAc-beta(1-2)Man-alpha(1-3)(GlcNAc-beta(1-2)Man-alpha(1-4))Man-beta(1-4)GlcNAc-2-amino pyridine Hep3B cell, pH 7.0, 37°C Homo sapiens
4.5
-
 UDP-GlcNAc Hep3B cell, pH 7.0, 37°C Homo sapiens
5.8
-
 UDP-GlcNAc Hep2G cell, pH 7.0, 37°C Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 induction of enzyme in hepatoma cells by treatment with retinoic acid and 1alpha2,5-dihydroxyvitamin D3, repression of enzyme by treatment with dimethyl sulfoxide or cytosine-arabinoside
-

Source Tissue

Source Tissue Comment Organism Textmining
HEP-3B cell
-
 Homo sapiens
-
Hep-G2 cell
-
 Homo sapiens
-
hepatocyte primary Homo sapiens
-
liver
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-GlcNAc + GlcNAc-beta(1-2)Man-alpha(1-3)(GlcNAc-beta(1-2)Man-alpha(1-4))Man-beta(1-4)GlcNAc-2-amino pyridine
-
 Homo sapiens ?
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
50
-
-
 Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.5
-
-
 Homo sapiens