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Literature summary for 2.4.1.152 extracted from
- A single amino acid in the hypervariable stem domain of vertebrate alpha1,3/1,4-fucosyltransferases determines the type 1/type 2 transfer. Characterization of acceptor substrate specificity of the Lewis enzyme by site-directed mutagenesis (1999), J. Biol. Chem., 274, 12257-12262.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| R115W/E116D | double mutation slightly increases H-type 1 activity | Bos taurus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | native enzyme utilizes only type 2 acceptors. Double mutation R115W/E116D slightly increases H-type 1 activity | Bos taurus | ? | - |
? |  |
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Release 2023.1 (January 2023)
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