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Literature summary for 2.4.1.152 extracted from

  • DeBose-Boyd, R.A.; Nyame, A.K.; Cummings, R.D.
    Schistosoma mansoni: characterization of an alpha 1-3 fucosyltransferase in adult parasites (1996), Exp. Parasitol., 82, 1-10.
    View publication on PubMed
Search for more literature for 2.4.1.152

Inhibitors

Inhibitors Comment Organism Structure
N-ethylmaleimide 14 mM causes 50% inhibition Schistosoma mansoni

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.3
-
 lacto-N-neotetraose
-
 Schistosoma mansoni

Metals/Ions

Metals/Ions Comment Organism Structure
Mn2+
-
 Schistosoma mansoni

Organism

Organism UniProt Comment Textmining
Schistosoma mansoni
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GDP-fucose + Galbeta1-4GlcNAc-R
-
 Schistosoma mansoni GDP + Galbeta1-4(Fucalpha1-3)GlcNAc-R Lewis x determinant ?
GDP-fucose + lacto-N-neotetraose
-
 Schistosoma mansoni GDP + lacto-N-fucopentaose III
-
 ?
GDP-fucose + NeuAcalpha2-3Galbeta1-4GlcNAc rate of reaction below 5% of the rate obtained toward nonsialylated acceptor Schistosoma mansoni GDP + NeuAcalpha2-3Galbeta1-4(Fucalpha1-3)GlcNAc sialyl Lewis x ?
additional information the enzyme does not transfer efficiently to the isomeric oligosaccharide lacto-N-tetraose Schistosoma mansoni ?
-
 ?
additional information the enzyme has acceptor specificity properties similar to that of the human myeloid enzyme FTIV Schistosoma mansoni ?
-
 ?