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Literature summary for 2.4.1.15 extracted from

  • Chen, Q.W.; Jin, S.; Zhang, L.; Shen, Q.D.; Wei, P.; Wei, Z.M.; Wang, S.G.; Tang, B.
    Regulatory functions of trehalose-6-phosphate synthase in the chitin biosynthesis pathway in Tribolium castaneum (Coleoptera Tenebrionidae) revealed by RNA interference (2018), Bull. Entomol. Res., 108, 388-399 .
    View publication on PubMed
Search for more literature for 2.4.1.15

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-alpha-D-glucose + D-glucose 6-phosphate Tribolium castaneum
-
 UDP + alpha,alpha-trehalose 6-phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Tribolium castaneum A0A139WIW2
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein the enzyme has two N-glycosylation sites Tribolium castaneum

Source Tissue

Source Tissue Comment Organism Textmining
epidermis low expression Tribolium castaneum
-
fat body highest expression Tribolium castaneum
-
malpighian tubule lowest expression Tribolium castaneum
-
midgut low expression Tribolium castaneum
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-alpha-D-glucose + D-glucose 6-phosphate
-
 Tribolium castaneum UDP + alpha,alpha-trehalose 6-phosphate
-
 ?

Subunits

Subunits Comment Organism
? x * 93070, calculated from amino acid sequence Tribolium castaneum

Synonyms

Synonyms Comment Organism
TPS
-
 Tribolium castaneum
TPS1 isoform Tribolium castaneum
TPS2 isoform Tribolium castaneum
trehalose-6-phosphate synthase
-
 Tribolium castaneum

pI Value

Organism Comment pI Value Maximum pI Value
Tribolium castaneum calculated from amino acid sequence
-
 6.6

General Information

General Information Comment Organism
malfunction silencing the enzyme gene leads to molting deformities and high mortality rates via regulation of gene expression in the chitin biosynthetic pathway Tribolium castaneum