Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.4.1.15 extracted from

  • An, M.Z.; Tang, Y.Q.; Mitsumasu, K.; Liu, Z.S.; Shigeru, M.; Kenji, K.
    Enhanced thermotolerance for ethanol fermentation of Saccharomyces cerevisiae strain by overexpression of the gene coding for trehalose-6-phosphate synthase (2011), Biotechnol. Lett., 33, 1367-1374.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
gene TPS1, Saccharomyces cerevisiae strain 10151 is used as host strain for transformation and overexpression, strains EP-1 and 14801 are used for preparing chromosomal DNAs Saccharomyces cerevisiae

Protein Variants

Protein Variants Comment Organism
additional information activity of T6P synthase and the accumulation of trehalose during ethanol fermentation are significantly improved by overexpression of TPS1, and especially at 38°C cmpared to 30°C, no obvious difference occurs in the activity of T6P synthase and the trehalose concentration for wild-type strain 10151, and transformed strains 10151-URA3 and 10151-pI-RED1, indicating that the expression of URA3 and YAP1 genes, markers of the expression plasmid, does not affect the synthesis of trehalose Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-alpha-D-glucose + D-glucose 6-phosphate Saccharomyces cerevisiae
-
UDP + alpha,alpha-trehalose 6-phosphate
-
?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
gene tps1
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-alpha-D-glucose + D-glucose 6-phosphate
-
Saccharomyces cerevisiae UDP + alpha,alpha-trehalose 6-phosphate
-
?

Synonyms

Synonyms Comment Organism
T6P synthase
-
Saccharomyces cerevisiae
TPS1
-
Saccharomyces cerevisiae
trehalose-6-phosphate synthase
-
Saccharomyces cerevisiae

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
35
-
assay at Saccharomyces cerevisiae