Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adrenal gland | - |
Mus musculus | - |
bone marrow | - |
Mus musculus | - |
brain | - |
Mus musculus | - |
colon | - |
Mus musculus | - |
heart | - |
Mus musculus | - |
kidney | - |
Mus musculus | - |
liver | - |
Mus musculus | - |
lung | - |
Mus musculus | - |
lymph node | - |
Mus musculus | - |
additional information | in wild type mice, GnT-IVa expression is restricted to gastrointestinal tissues, whereas GnT-IVb is broadly expressed among organs | Mus musculus | - |
muscle | - |
Mus musculus | - |
ovary | - |
Mus musculus | - |
pancreas | - |
Mus musculus | - |
small intestine | - |
Mus musculus | - |
spleen | - |
Mus musculus | - |
stomach | - |
Mus musculus | - |
testis | - |
Mus musculus | - |
thymus | - |
Mus musculus | - |
uterus | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-N-acetyl-D-glucosamine + GlcNAcbeta1-2Manalpha1-6(GlcNAcbeta1-2Manalpha1-3)Manbeta1-4GlcNAcbeta1-4GlcNAc-2-aminopyridine | isozyme GnT-IVb has about 30% activity of isozyme GnT-IVa | Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
GnT-IVa | isozyme | Mus musculus |
GnT-IVb | isozyme | Mus musculus |
N-acetylglucosaminyltransferase-IVa | isozyme | Mus musculus |
N-acetylglucosaminyltransferase-IVb | isozyme | Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | isozyme GnT-IVb deficiency shows mild phenotypic alterations in hematopoietic cell populations and hemostasis, GnT-IVa/-IVb double deficiency completely abolishes GnT-IV activity that results in the disappearance of the GlcNAcbeta1-4 branch on the Manalpha1-3 arm | Mus musculus |