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Literature summary for 2.4.1.135 extracted from

  • Venkatesan, N.; Ouzzine, M.; Kolb, M.; Netter, P.; Ludwig, M.S.
    Increased deposition of chondroitin/dermatan sulfate glycosaminoglycan and upregulation of beta1,3-glucuronosyltransferase I in pulmonary fibrosis (2011), Am. J. Physiol. Lung Cell Mol. Physiol., 300, L191-L203.
    View publication on PubMed
Search for more literature for 2.4.1.135

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
43000
-
 x * 43000, SDS-PAGE Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
lung
-
 Rattus norvegicus
-
lung fibroblast
-
 Rattus norvegicus
-

Subunits

Subunits Comment Organism
? x * 43000, SDS-PAGE Rattus norvegicus

Synonyms

Synonyms Comment Organism
beta1,3-glucuronosyltransferase I
-
 Rattus norvegicus
GlcAT-I
-
 Rattus norvegicus

Expression

Organism Comment Expression
Rattus norvegicus the enzyme is upregulated 3fold by 5 ng/ml transforming growth factor-beta1. Enzyme expression is increased in idiopathic pulmonary fibrosis, fibrotic rat lungs, and fibrotic lung fibroblasts up

General Information

General Information Comment Organism
metabolism the enzyme is a key regulator and rate-limiting enzyme for the synthesis of GAG chains Rattus norvegicus