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Literature summary for 2.4.1.133 extracted from

  • Higuchi, T.; Tamura, S.; Tanaka, K.; Takagaki, K.; Saito, Y.; Endo, M.
    Effects of ATP on regulation of galactosyltransferase-I activity responsible for synthesis of the linkage region between the core protein and glycosaminoglycan chains of proteoglycans (2001), Biochem. Cell Biol., 79, 159-164.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
ATP results suggest that a protein kinase in the 100000 x g supernatant activates galactosyltransferase I Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.33
-
4-methylumbelliferyl-beta-D-xyloside pH 5.5, 37°C after preincubation with ATP Homo sapiens
0.34
-
UDPgalactose pH 5.5, 37°C after preincubation with ATP Homo sapiens
0.41
-
UDPgalactose pH 5.5, 37°C before preincubation with ATP Homo sapiens
0.5
-
4-methylumbelliferyl-beta-D-xyloside pH 5.5, 37°C before preincubation with ATP Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
skin fibroblast
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDPgalactose + 4-methylumbelliferyl-beta-D-xyloside
-
Homo sapiens UDP + beta-D-galactosyl-1,4-beta-D-xylosyl-1-O-(4-methylumbelliferone)
-
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