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Literature summary for 2.4.1.132 extracted from
- A unique alpha-1,3-mannosyltransferase of the pathogenic fungus Cryptococcus neoformans (1999), J. Bacteriol., 181, 5482-5488.
Application
| Application | Comment | Organism |
|---|---|---|
| pharmacology | target for antifungal drug discovery | Cryptococcus neoformans |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| GDP | - |
Cryptococcus neoformans |  |
| mannose-1-phosphate | - |
Cryptococcus neoformans | |
| additional information | not inhibited by amphomycin or tunicamycin | Cryptococcus neoformans |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | - |
Cryptococcus neoformans | 16020 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Cryptococcus neoformans | role in the synthesis of the glucuronoxylomannan of the capsule | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Cryptococcus neoformans | - |
pathogenic fungus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | role in the synthesis of the glucuronoxylomannan of the capsule | Cryptococcus neoformans | ? | - |
? | |
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