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Literature summary for 2.4.1.12 extracted from

  • Basu, S.; Omadjela, O.; Gaddes, D.; Tadigadapa, S.; Zimmer, J.; Catchmark, J.
    Cellulose microfibril formation by surface-tethered cellulose synthase enzymes (2016), ACS Nano, 10, 1896-1907 .
    View publication on PubMed
Search for more literature for 2.4.1.12

Activating Compound

Activating Compound Comment Organism Structure
cyclic diguanylate allosteric activator, required for catalytic activity Cereibacter sphaeroides

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli C41 cells Cereibacter sphaeroides

Inhibitors

Inhibitors Comment Organism Structure
EDTA
-
 Cereibacter sphaeroides

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required for catalytic activity Cereibacter sphaeroides

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-alpha-D-glucose + [(1->4)-beta-D-glucosyl]n Cereibacter sphaeroides
-
 UDP + [(1->4)-beta-D-glucosyl]n+1
-
 ?

Organism

Organism UniProt Comment Textmining
Cereibacter sphaeroides
-
-
-

Purification (Commentary)

Purification (Comment) Organism
Ni-NTA agarose column chromatography Cereibacter sphaeroides

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-alpha-D-glucose + [(1->4)-beta-D-glucosyl]n
-
 Cereibacter sphaeroides UDP + [(1->4)-beta-D-glucosyl]n+1
-
 ?

Subunits

Subunits Comment Organism
? x * 164000, SDS-PAGE Cereibacter sphaeroides

Synonyms

Synonyms Comment Organism
BcsA-B
-
 Cereibacter sphaeroides

General Information

General Information Comment Organism
metabolism in the presence of required substrate (UDP-alpha-D-glucose) and all cofactors (cyclic diguanylate and Mg2+), the enzyme efficiently synthesizes cellulose microfibrils Cereibacter sphaeroides