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Literature summary for 2.4.1.11 extracted from

  • Wilson, W.A.; Pradhan, P.; Madhan, N.; Gist, G.C.; Brittingham, A.
    Glycogen synthase from the parabasalian parasite Trichomonas vaginalis An unusual member of the starch/glycogen synthase family (2017), Biochimie, 138, 90-101 .
    View publication on PubMed
Search for more literature for 2.4.1.11

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli strain BL21(DE3) and in Saccharomyces cerevisiae strain WW100 lacking endogenous glycogen synthase activity Trichomonas vaginalis

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.056
-
 UDP-glucose at pH 7.8, temperature not specified in the publication Trichomonas vaginalis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-glucose + glycogen Trichomonas vaginalis
-
 UDP + ?
-
 ?
UDP-glucose + glycogen Trichomonas vaginalis ATCC PRA-98
-
 UDP + ?
-
 ?

Organism

Organism UniProt Comment Textmining
Trichomonas vaginalis
-
-
-
Trichomonas vaginalis ATCC PRA-98
-
-
-

Purification (Commentary)

Purification (Comment) Organism
Bio-Scale Mini Profinity IMAC Trichomonas vaginalis

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.5
-
 at pH 7.8, temperature not specified in the publication Trichomonas vaginalis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme is not able to transfer glucose from UDP-glucose to glucose itself Trichomonas vaginalis ?
-
-
additional information the enzyme is not able to transfer glucose from UDP-glucose to glucose itself Trichomonas vaginalis ATCC PRA-98 ?
-
-
UDP-glucose + glycogen
-
 Trichomonas vaginalis UDP + ?
-
 ?
UDP-glucose + glycogen
-
 Trichomonas vaginalis ATCC PRA-98 UDP + ?
-
 ?
UDP-glucose + maltoheptaose
-
 Trichomonas vaginalis UDP + ?
-
 ?
UDP-glucose + maltoheptaose
-
 Trichomonas vaginalis ATCC PRA-98 UDP + ?
-
 ?
UDP-glucose + maltose
-
 Trichomonas vaginalis UDP + ?
-
 ?
UDP-glucose + maltose
-
 Trichomonas vaginalis ATCC PRA-98 UDP + ?
-
 ?
UDP-glucose + maltotetraose
-
 Trichomonas vaginalis UDP + ?
-
 ?
UDP-glucose + maltotetraose
-
 Trichomonas vaginalis ATCC PRA-98 UDP + ?
-
 ?
UDP-glucose + maltotriose
-
 Trichomonas vaginalis UDP + ?
-
 ?

Subunits

Subunits Comment Organism
? x * 56000, SDS-PAGE Trichomonas vaginalis

Synonyms

Synonyms Comment Organism
glycogen synthase
-
 Trichomonas vaginalis
starch/glycogen synthase
-
 Trichomonas vaginalis
TVAG_258220 open reading frame Trichomonas vaginalis