Activating Compound | Comment | Organism | Structure |
---|---|---|---|
glucose 6-phosphate | synthase D, i.e. phosphorylated form, is glucose 6-phosphate dependent, synthase I, i.e. dephosphorylated form, is glucose 6-phosphate independent, interconversion of D and I forms and vice versa | Oryctolagus cuniculus |
General Stability | Organism |
---|---|
freezing leads to loss of activity | Oryctolagus cuniculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
beta-Glycerophosphate | - |
Oryctolagus cuniculus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
85000 | - |
2 * 85000, SDS-PAGE | Oryctolagus cuniculus |
170000 | - |
synthase I, sucrose density gradient centrifugation | Oryctolagus cuniculus |
183000 | - |
synthase D, sucrose density gradient centrifugation | Oryctolagus cuniculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-glucose + glycogen | Oryctolagus cuniculus | - |
glycogen + UDP | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Oryctolagus cuniculus | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | incorporation of 1.13 mol phosphate per subunit | Oryctolagus cuniculus |
phosphoprotein | phosphorylation leads to loss of activity | Oryctolagus cuniculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Oryctolagus cuniculus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
25 | - |
- |
Oryctolagus cuniculus |
Storage Stability | Organism |
---|---|
-70°C, beta-glycerophosphate buffer, 1 year | Oryctolagus cuniculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-glucose + glycogen | - |
Oryctolagus cuniculus | glycogen + UDP | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | 2 * 85000, SDS-PAGE | Oryctolagus cuniculus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | - |
- |
Oryctolagus cuniculus |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
25 | - |
stable in imidazole or beta-glycerophosphate buffer, instable in Tris or glycylglycine buffer | Oryctolagus cuniculus |