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Literature summary for 2.4.1.1 extracted from
- Seasonality of glycogen phosphorylase activity in crucian carp (Carassius carassius L.) (2011), J. Comp. Physiol. B, 181, 917-926.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| AMP | - |
Carassius carassius |  |
| additional information | anoxia (or ischemia) results in the rapid activation of glycogen phosphorylase | Carassius carassius |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| [(1->4)-alpha-D-glucosyl]n + phosphate | Carassius carassius | - |
[(1->4)-alpha-D-glucosyl]n-1 + alpha-D-glucose 1-phosphate | - |
r | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Carassius carassius | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| phosphoprotein | the glycogen phosphorylase dimer can exist in either in unphosphorylated glycogen phosphorylase b or phosphorylated glycogen phosphorylase a form depending on hormonal activation of kinase/phosphatase reactions | Carassius carassius |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Carassius carassius | - |
| heart | - |
Carassius carassius | - |
| liver | - |
Carassius carassius | - |
| additional information | when seasonal temperature changes are taken into account, the activity of GP during the anoxic midwinter is only 4-6% of its summer time activity in the muscle, heart and liver, and 13% in brain | Carassius carassius | - |
| muscle | - |
Carassius carassius | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| [(1->4)-alpha-D-glucosyl]n + phosphate | - |
Carassius carassius | [(1->4)-alpha-D-glucosyl]n-1 + alpha-D-glucose 1-phosphate | - |
r | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| glycogen phosphorylase | - |
Carassius carassius |
| GPA | - |
Carassius carassius |
| GPb | - |
Carassius carassius |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 25 | - |
- |
Carassius carassius |
Temperature Range [°C]
| Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 5 | 35 | in the tissues, except the gill, the basal and total activities of glycogen phosphorylase increase from 5 to 25°C, but less steeply between 5 and 15°C than between 15 and 25°C, inactivation starts above 25°C | Carassius carassius |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6.1 | - |
assay at | Carassius carassius |
General Information
| General Information | Comment | Organism |
|---|---|---|
| additional information | the glycogen phosphorylase dimer can exist in either in unphosphorylated glycogen phosphorylase b or phosphorylated glycogen phosphorylase a form depending on hormonal activation of kinase/phosphatase reactions | Carassius carassius |
| physiological function | glycogen phosphorylase is a rate-limiting enzyme of glycogen degradation | Carassius carassius |
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Release 2023.1 (January 2023)
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