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Literature summary for 2.4.1.1 extracted from
- Mastoparan binds to glycogen phosphorylase to regulate sarcoplasmic reticular Ca2+ release in skeletal muscle (2003), Biochem. J., 371, 81-88.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytoplasm | - |
Oryctolagus cuniculus | 5737 | - |
| sarcoplasmic reticulum | mastoparan dissociates the enzyme from the heavy fraction of the sarcoplasmic reticulum, i.e. HSR | Oryctolagus cuniculus | 16529 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 97000 | - |
x * 97000, SDS-PAGE | Oryctolagus cuniculus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Oryctolagus cuniculus | mastoparan binds to the enzyme to negatively regulate sarcoplasmic reticular Ca2+ release in skeletal muscle involving the ryanodine receptor, overview | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Oryctolagus cuniculus | P00489 | - |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| from muscle, to homogeneity by several chromatographic steps and preparative SDS-PAGE | Oryctolagus cuniculus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| skeletal muscle | - |
Oryctolagus cuniculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | mastoparan binds to the enzyme to negatively regulate sarcoplasmic reticular Ca2+ release in skeletal muscle involving the ryanodine receptor, overview | Oryctolagus cuniculus | ? | - |
? | |
| additional information | the enzyme specifically binds to mastoparan, a wasp venom toxin | Oryctolagus cuniculus | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 97000, SDS-PAGE | Oryctolagus cuniculus |
| More | proteolytic digestion pattern, amino acid sequence determination | Oryctolagus cuniculus |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| glycogen phosphorylase | - |
Oryctolagus cuniculus |
| GP | - |
Oryctolagus cuniculus |
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Release 2023.1 (January 2023)
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