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Literature summary for 2.4.1.1 extracted from

  • Spearman, T.N.; Khandelwal, R.L.; Hamilton, I.R.
    Some regulatory properties of glycogen phosphorylase from Streptococcus salivarius (1973), Arch. Biochem. Biophys., 154, 306-313.
    View publication on PubMed
Search for more literature for 2.4.1.1

Activating Compound

Activating Compound Comment Organism Structure
5'-AMP activation Streptococcus salivarius
5'-AMP slight activation Streptococcus salivarius
5'-AMP inhibition of phosphorolysis at 2 mM and above Streptococcus salivarius
5'-AMP significant activation by synergism with NaF, glycogen as substrate, inhibition above 2 mM Streptococcus salivarius
ADP activation, in the absence of AMP Streptococcus salivarius
ADP-glucose 170% activation of glycogen synthesis in the absence of AMP and NaF, 68% inhibition in the presence of AMP and NaF Streptococcus salivarius
ATP activation Streptococcus salivarius
ATP no activation of synthesis Streptococcus salivarius
cAMP activation Streptococcus salivarius
cAMP in the absence of AMP, inhibition at 5 mM Streptococcus salivarius

Inhibitors

Inhibitors Comment Organism Structure
ADPglucose
-
 Streptococcus salivarius
AMP above 2 mM Streptococcus salivarius
cAMP 5 mM, weak inhibition Streptococcus salivarius
D-glucose weak Streptococcus salivarius

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information
-
 Streptococcus salivarius
0.125
-
 AMP glycogen synthesis, in the presence of NaF Streptococcus salivarius
0.25
-
 AMP glycogen synthesis Streptococcus salivarius
0.49
-
 KF glycogen synthesis Streptococcus salivarius

Metals/Ions

Metals/Ions Comment Organism Structure
NaF slight Streptococcus salivarius
NaF significant activation by synergism with AMP, glycogen as substrate Streptococcus salivarius

Organism

Organism UniProt Comment Textmining
Streptococcus salivarius
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(dextrin)n-1 + glucose 1-phosphate
-
 Streptococcus salivarius (dextrin)n + phosphate
-
 r
glycogen + glucose 1-phosphate glycogen from oyster Streptococcus salivarius glycogen + phosphate
-
 r
glycogen + glucose 1-phosphate glycogen from: oyster Streptococcus salivarius glycogen + phosphate
-
 r
[(1->4)-alpha-D-glucosyl]n + phosphate polyglucose primer required Streptococcus salivarius [(1->4)-alpha-D-glucosyl]n-1 + alpha-D-glucose 1-phosphate
-
 r