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Literature summary for 2.3.3.8 extracted from
- Analysis of ATP-citrate lyase and malic enzyme mutants of Yarrowia lipolytica points out the importance of mannitol metabolism in fatty acid synthesis (2015), Biochim. Biophys. Acta, 1851, 1107-1117.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Yarrowia lipolytica | 5829 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ADP + phosphate + acetyl-CoA + oxaloacetate | Yarrowia lipolytica | - |
ATP + citrate + CoA | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Yarrowia lipolytica | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ADP + phosphate + acetyl-CoA + oxaloacetate | - |
Yarrowia lipolytica | ATP + citrate + CoA | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ACL | - |
Yarrowia lipolytica |
| ATP-citrate lyase | - |
Yarrowia lipolytica |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | enzyme inactivation decreases fatty acid synthesis by 60 to 80% | Yarrowia lipolytica |
| metabolism | the enzyme plays an essential role in fatty acid synthesis | Yarrowia lipolytica |
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Release 2023.1 (January 2023)
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