Literature summary for 2.3.3.8 extracted from

Ki, S.W.; Ishigami, K.; Kitahara, T.; Kasahara, K.; Yoshida, M.; Horinouchi, S.
Radicicol binds and inhibits mammalian ATP citrate lyase (2000), J. Biol. Chem., 275, 39231-39236.

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Inhibitors

Inhibitors	Comment	Organism	Structure
radicicol	noncompetitive	Rattus norvegicus
radicicol biotinylated at the C-17 position	no inhibition with the derivative biotinylated at the C-18 position	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
HeLa cell	-	Homo sapiens	-
liver	-	Homo sapiens	-
liver	-	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + citrate + CoA	-	Homo sapiens	ADP + phosphate + acetyl-CoA + oxaloacetate	-	?
ATP + citrate + CoA	-	Rattus norvegicus	ADP + phosphate + acetyl-CoA + oxaloacetate	-	?

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Release 2023.1 (January 2023)